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Tbio
PITPNB
Phosphatidylinositol transfer protein beta isoform

Protein Summary
Description
Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes. This gene encodes a cytoplasmic protein that catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes. This transfer activity is required for COPI complex-mediated retrograde transport from the Golgi apparatus to the endoplasmic reticulum. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000320996
  • ENSP00000321266
  • ENSG00000180957
  • ENST00000335272
  • ENSP00000334738
  • ENST00000634017
  • ENSP00000487693

Symbol
  • VIB1B
  • PtdInsTP
  • PI-TP-beta
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
1
disease perturbation
0.98
kinase perturbation
0.96
histone modification site profile
0.87
interacting protein
0.86


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 41.02   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 249   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 41.02   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 249   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0