Tchem NPBWR1 Neuropeptides B/W receptor type 1

Protein Summary

Description

Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals. Has a higher affinity for neuropeptide B.

Uniprot Accession IDs

• P48145
• Q6NTC7

Gene Name

• NPBWR1

Ensembl ID

• ENST00000331251
• ENSP00000330284
• ENSG00000183729

Symbol

• GPR7
• GPR7

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.6
protein domain	0.58
histone modification site profile	0.57
cell line	0.56
tissue	0.53

Protein Classes

PANTHER Classes

Protein / Receptor / G-protein Coupled Receptor / Neuropeptides B/w Receptor Type 1

DTO Classes

Protein / G-protein Coupled Receptor / Class A Rhodopsin Like / Neuropeptide W/neuropeptide B Receptor / Neuropeptides B/w Receptor Type 1

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 35.57   (req: < 5)

Gene RIFs: 9   (req: <= 3)

Antibodies: 207   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 35.57   (req: >= 5)

Gene RIFs: 9   (req: > 3)

Antibodies: 207   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 11

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0