Property Summary

NCBI Gene PubMed Count 10
PubMed Score 12.05
PubTator Score 97.82

Knowledge Summary

Patent (430)

TINX Plot

  Disease Relevance (1)

Disease Z-score Confidence
diabetes mellitus 1,663

Gene RIF (2)

PMID Text
17579849 This work shows the feasibility of an olfactory biosensor based on the immobilization of Saccharomyces cerevisiae yeast cells genetically modified to express the human olfactory receptor OR17-40
16980412 This unique mechanism of continuous internalization and recycling of OR17-40 might be instrumental in allowing rapid recovery of odor perception.

AA Sequence

MQPESGANGTVIAEFILLGLLEAPGLQPVVFVLFLFAYLVTVRGNLSILAAVLVEPKLHTPMYFFLGNLS      1 - 70
VLDVGCISVTVPSMLSRLLSRKRAVPCGACLTQLFFFHLFVGVDCFLLTAMAYDRFLAICRPLTYSTRMS     71 - 140
QTVQRMLVAASWACAFTNALTHTVAMSTLNFCGPNVINHFYCDLPQLFQLSCSSTQLNELLLFAVGFIMA    141 - 210
GTPMALIVISYIHVAAAVLRIRSVEGRKKAFSTCGSHLTVVAIFYGSGIFNYMRLGSTKLSDKDKAVGIF    211 - 280
NTVINPMLNPIIYSFRNPDVQSAIWRMLTGRRSLA                                       281 - 315
//

Text Mined References (11)

PMID Year Title
23958962 2014 Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.
17579849 2007 A new concept of olfactory biosensor based on interdigitated microelectrodes and immobilized yeasts expressing the human receptor OR17-40.
16980412 2006 Visualizing odorant receptor trafficking in living cells down to the single-molecule level.
16625196 2006 DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
15489334 2004 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
14983052 2004 The human olfactory receptor gene family.
12477932 2002 Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
10673334 2000 Sequence, structure, and evolution of a complete human olfactory receptor gene cluster.
8921386 1996 Sequence analysis in the olfactory receptor gene cluster on human chromosome 17: recombinatorial events affecting receptor diversity.
8647456 1996 Olfactory receptor-encoding genes and pseudogenes are expressed in humans.
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