Property Summary

NCBI Gene PubMed Count 45
PubMed Score 63.00
PubTator Score 52.87

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Sources (2)

Expression

Synonym

Accession P43487 Q53EY3
Symbols HTF9A

Gene

PANTHER Protein Class (2)

PDB

1K5D   1K5G  

  Ortholog (14)

Species Source
Chimp OMA EggNOG
Macaque OMA EggNOG Inparanoid
Mouse OMA EggNOG Inparanoid
Rat OMA EggNOG Inparanoid
Dog EggNOG Inparanoid
Horse OMA EggNOG
Cow OMA EggNOG
Pig EggNOG Inparanoid
Platypus OMA EggNOG
Chicken OMA Inparanoid
Anole lizard OMA EggNOG Inparanoid
Xenopus OMA EggNOG Inparanoid
Zebrafish OMA EggNOG Inparanoid
S.cerevisiae EggNOG Inparanoid

Gene RIF (15)

PMID Text
23108393 Sgk1-dependent regulation of RANBP1 has functional consequences on both mitotic microtubule activity and taxol sensitivity of cancer cells.
22190034 HIV-1 Vpu is identified to have a physical interaction with RAN binding protein 1 (RANBP1) in human HEK293 and/or Jurkat cell lines by using affinity tagging and purification mass spectrometry analyses
21813642 in vitro and in vivo phosphorylation of RanBP1 by Plk1 as well as the importance of phosphorylation of RanBP1 in the interaction between Plk1 and Ran during early mitosis, is demonstrated.
21184585 RANBP1 on 22q11.21 locus might be causally related to the smooth pursuit eye movement abnormality rather than the development of schizophrenia.
20658144 Downregulation of the Ran GTPase effector RanBP1 is required for nuclear reorganisation.
20508983 Observational study of gene-disease association. (HuGE Navigator)
19549784 Generation of Ran-GTP from Ran-GDP by importin-beta is activated by Ran-binding protein-1 (RanBP1) that forms a trimeric complex with Ran-GDP and importin-beta.
19270727 RanBP1-interfered cells show an increased apoptotic response to taxol compared to their counterpart with normal or high RanBP1 levels, and this response is caspase-3 dependent.
19149558 HIV-1 Vpu is identified to have a physical interaction with RAN binding protein 1 (RANBP1) in human HEK293 and/or Jurkat cell lines by using affinity tagging and purification mass spectrometry analyses
18187620 HIV-1 Vpu is identified to have a physical interaction with RAN binding protein 1 (RANBP1) in human HEK293 and/or Jurkat cell lines by using affinity tagging and purification mass spectrometry analyses
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AA Sequence

MAAAKDTHEDHDTSTENTDESNHDPQFEPIVSLPEQEIKTLEEDEEELFKMRAKLFRFASENDLPEWKER      1 - 70
GTGDVKLLKHKEKGAIRLLMRRDKTLKICANHYITPMMELKPNAGSDRAWVWNTHADFADECPKPELLAI     71 - 140
RFLNAENAQKFKTKFEECRKEIEEREKKAGSGKNDHAEKVAEKLEALSVKEETKEDAEEKQ             141 - 201
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Text Mined References (60)

PMID Year Title
25944712 2015 N-terminome analysis of the human mitochondrial proteome.
25772364 2015 SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage.
25743254 2015 Proteomic analyses reveal that loss of TDP-43 affects RNA processing and intracellular transport.
25468996 2014 E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
25218447 2014 Uncovering global SUMOylation signaling networks in a site-specific manner.
25114211 2014 Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.
24275569 2014 An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
23186163 2013 Toward a comprehensive characterization of a human cancer cell phosphoproteome.
23108393 2013 Sgk1 enhances RANBP1 transcript levels and decreases taxol sensitivity in RKO colon carcinoma cells.
21998203 2011 Induction of Ran GTP drives ciliogenesis.
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