Property Summary

NCBI Gene PubMed Count 1,840
Grant Count 2,446
R01 Count 1,453
Funding $253,301,917.68
PubMed Score 5706.63
PubTator Score 3667.37

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Relevance (87)

Disease Z-score Confidence
Cancer 2,346 6.944 3.5
Job's syndrome 4 5.855 2.9
Inflammatory bowel disease 142 4.98 2.5
Obesity 616 4.832 2.4
Vascular disease 281 4.764 2.4
Arthritis 248 4.253 2.1
Dermatitis 107 4.115 2.1
psoriasis 6,685 3.856 1.9
Liver disease 219 3.754 1.9
Hypersensitivity reaction type II diseas... 235  3.64 1.8
diabetes mellitus 1,663 3.6 1.8
Candidiasis 48 3.328 1.7
Kidney disease 396 3.306 1.7
Pneumonia 133 3.222 1.6
Multiple Sclerosis 498 3.213 1.6
Eye disease 55 3.206 1.6
Asthma 349 3.082 1.5
Heart disease 279 3.056 1.5
Pancreatitis 97 3.013 1.5
AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTI... 1 
Adenocarcinoma 115
Adult T-Cell Lymphoma/Leukemia 30
Animal Mammary Neoplasms 136
Arthritis, Experimental 39
Atherosclerosis 275
Atopic dermatitis 944
Atrophic 10
Autoimmune Diseases 33
Brain Ischemia 87
Cardiomegaly 66
Cardiomyopathies 90
Colonic Neoplasms 126
Copper-Overload Cirrhosis 11
Crohn Disease 97
Crohn's disease 304 2.0
Diabetes Mellitus, Insulin-Dependent 76
Diphyllobothrium Infections 1
Fibrosis 40
Hepatitis, Chronic 22
Hymenolepiasis Infections 1
Hyper-Ige Recurrent Infection Syndrome, ... 1 
Hyper-Immunoglobulin E Syndrome, Autosom... 1 
Immune system cancer 38 1.0
Infarction, Middle Cerebral Artery 25
Inflammation 109
Inflammatory Bowel Diseases 87
Job Syndrome 3
Juvenile arthritis 124
Ki-1+ Anaplastic Large Cell Lymphoma 4
Leukemia, Myelocytic, Acute 113
Leukemia, T-Cell 5
Liver neoplasms 109
Lymphatic Metastasis 14
Lymphoid leukemia 69 1.0
Mammary Neoplasms 410
Mammary Neoplasms, Experimental 150
Memory Disorders 36
Multiple myeloma 1,327
Neoplasm Metastasis 138
Pancreatic Neoplasm 79
Precursor B-Cell Lymphoblastic Leukemia-... 11 
Prostate cancer 172 5.0
Prostatic Neoplasms 471
Reperfusion Injury 84
Rheumatoid Arthritis 1,160
Squamous cell carcinoma 94
Stomach Neoplasms 282
T-Cell Lymphoma 11
Taenia Infection 1
Uterine Cervical Neoplasm 21
adult high grade glioma 2,148
astrocytoma 1,493
atypical teratoid / rhabdoid tumor 4,369
ependymoma 2,514
glioblastoma 5,572
intraductal papillary-mucinous neoplasm ... 3,289 
lung adenocarcinoma 2,713
lung cancer 4,466
medulloblastoma 1,524
non-small cell lung carcinoma 413
osteosarcoma 7,933
ovarian cancer 8,484
ovarian neoplasm 97
pancreatic ductal adenocarcinoma liver m... 1,795 
pilocytic astrocytoma 3,086
pituitary cancer 1,972
ulcerative colitis 2,087

Expression

  Differential Expression (18)

Disease log2 FC p
psoriasis 1.800 0.000
Rheumatoid Arthritis 1.700 0.006
Multiple myeloma 1.402 0.010
glioblastoma 2.200 0.006
osteosarcoma 2.370 0.000
ependymoma 1.100 0.000
astrocytoma 2.300 0.001
atypical teratoid / rhabdoid tumor 1.300 0.000
Crohn's disease 1.021 0.005
Atopic dermatitis 1.200 0.002
pancreatic ductal adenocarcinoma liver m... -1.832 0.003
intraductal papillary-mucinous neoplasm ... -1.100 0.002
lung cancer -1.900 0.000
adult high grade glioma 1.200 0.000
pilocytic astrocytoma 1.100 0.000
lung adenocarcinoma 1.072 0.001
ovarian cancer 2.500 0.000
pituitary cancer -2.200 0.000

Synonym

Accession P40763 A8K7B8 K7ENL3 O14916 Q9BW54
Symbols APRF
HIES
ADMIO
ADMIO1

Gene

PANTHER Protein Class (1)