Property Summary

NCBI Gene PubMed Count 2,266
Grant Count 2,322
R01 Count 1,174
Funding $408,902,703.85
PubMed Score 5756.80
PubTator Score 6429.25

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Relevance (50)

Disease Z-score Confidence
Cancer 2,346 7.413 3.7
Hereditary breast ovarian cancer 6 6.064 3.0
Lynch syndrome 33 4.706 2.4
Li-Fraumeni Syndrome 13 4.589 2.3
ductal carcinoma in situ 1,745 4.046 2.0
Anemia 252 3.987 2.0
Ataxia telangiectasia 31 3.981 2.0
Lobular neoplasia 15 3.607 1.8
Cowden disease 16 3.506 1.8
Nijmegen breakage syndrome 23 3.406 1.7
Breast disease 8 3.155 1.6
Premature menopause 7 3.154 1.6
Adenoid Cystic Carcinoma 99
Animal Mammary Neoplasms 136
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPT... 7 
Breast Cancer, Familial 12
Breast cancer 3,094 5.0
Carcinoma 2,147 1.0
Chromosome Breakage 5
FANCONI ANEMIA, COMPLEMENTATION GROUP A ... 2 
Hereditary Breast and Ovarian Cancer Syn... 14 
Malignant neoplasm of breast 63
Malignant neoplasm of ovary 13
Mammary Neoplasms 410
Mammary Neoplasms, Experimental 150
Mouth Diseases 12
Neoplastic Cell Transformation 81
Neoplastic Syndromes, Hereditary 48
PANCREATIC CANCER, SUSCEPTIBILITY TO, 4 1
Pancreatic Neoplasm 79
Pancreatic carcinoma, familial 8
Peripheral Neuropathy 303
Prostate cancer 172 5.0
Prostate cancer, familial 13
Prostatic Neoplasms 471
colon cancer 1,475
glioblastoma 5,572
group 3 medulloblastoma 2,254
intraductal papillary-mucinous carcinoma... 2,988 
intraductal papillary-mucinous neoplasm ... 3,289 
lung adenocarcinoma 2,713
lung cancer 4,466
malignant mesothelioma 3,162
medulloblastoma, large-cell 6,234
nasopharyngeal carcinoma 1,056
non-small cell lung cancer 2,798
osteosarcoma 7,933
ovarian neoplasm 97
posterior fossa group A ependymoma 1,511
primitive neuroectodermal tumor 3,031

Expression

Synonym

Accession P38398 E9PFZ0 O15129 Q1RMC1 Q3LRJ0 Q3LRJ6 Q6IN79 Q7KYU9
Symbols IRIS
PSCP
BRCAI
BRCC1
FANCS
PNCA4
RNF53
BROVCA1
PPP1R53

Gene

PANTHER Protein Class (2)