Property Summary

NCBI Gene PubMed Count 1,251
Grant Count 2,478
R01 Count 933
Funding $462,364,370.03
PubMed Score 3997.26
PubTator Score 4085.41

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Relevance (68)

Disease Z-score Confidence
Parkinson's disease 364 8.23 4.0
Multiple system atrophy 27 7.023 3.5
Dementia 129 6.613 3.3
Alzheimer's disease 644 5.439 2.7
Brain disease 83 4.939 2.5
Toxic encephalopathy 131 4.752 2.4
Chromosome 3q29 microdeletion syndrome 8 4.553 2.3
Cancer 2,346 4.53 2.3
Optic atrophy 43 4.157 2.1
Pick's disease 14 4.07 2.0
REM sleep behavior disorder 16 4.068 2.0
Huntington's disease 72 3.686 1.8
Intellectual disability 573 3.659 1.8
Chromosome 3q29 microduplication syndrom... 6  3.649 1.8
Amyotrophic Lateral Sclerosis 431 3.565 1.8
Cornelia de Lange syndrome 21 3.486 1.7
Pantothenate kinase-associated neurodege... 15  3.452 1.7
Gaucher's disease 24 3.413 1.7
Olivopontocerebellar atrophy 9 3.211 1.6
Scotoma 7 3.175 1.6
Autistic Disorder 320 3.045 1.5
Balkan Nephropathy 6 3.008 1.5
Alcoholic Intoxication, Chronic 41
Amphetamine-Related Disorders 74
Breast cancer 3,094
Cocaine-Related Disorders 88
Gaucher Disease 4
Hepatolenticular Degeneration 24
Lameness, Animal 1
Lewy Body Disease 19
Manganese Poisoning 11
Nerve Degeneration 73
Neurodegenerative Disorders 37
Neurodegenerative disease 383 4.0
PARKINSON DISEASE 1, AUTOSOMAL DOMINANT ... 1 
PARKINSON DISEASE 4, AUTOSOMAL DOMINANT ... 1 
Parkinson Disease 102
Parkinsonian Disorders 23
Pick disease 1,893
Psychoses, Substance-Induced 17
astrocytic glioma 2,241
atypical teratoid / rhabdoid tumor 4,369
breast carcinoma 1,614
colon cancer 1,475
cutaneous lupus erythematosus 1,056
ependymoma 2,514
glioblastoma 5,572
head and neck cancer and chronic obstruc... 237 
intraductal papillary-mucinous adenoma (... 2,956 
invasive ductal carcinoma 2,950
lung adenocarcinoma 2,713
lung cancer 4,466
malignant mesothelioma 3,162
medulloblastoma 1,524
medulloblastoma, large-cell 6,234
non primary Sjogren syndrome sicca 840
non-small cell lung carcinoma 413
oligodendroglioma 2,849
osteosarcoma 7,933
ovarian cancer 8,484
pancreatic cancer 2,300
pancreatic carcinoma 567
pediatric high grade glioma 2,712
pilocytic astrocytoma 3,086
primitive neuroectodermal tumor 3,031
psoriasis 6,685
tuberculosis 1,557
urothelial carcinoma 318

Expression

  Differential Expression (30)

Disease log2 FC p
pancreatic cancer 1.600 0.000
urothelial carcinoma -1.800 0.000
malignant mesothelioma -4.600 0.000
astrocytic glioma -4.200 0.002
ependymoma -4.500 0.002
oligodendroglioma -3.300 0.011
cutaneous lupus erythematosus -1.300 0.004
psoriasis -1.500 0.000
glioblastoma -5.400 0.000
osteosarcoma -4.414 0.001
medulloblastoma -4.600 0.000
atypical teratoid / rhabdoid tumor -5.500 0.000
medulloblastoma, large-cell -5.900 0.000
primitive neuroectodermal tumor -3.500 0.000
tuberculosis 1.600 0.001
intraductal papillary-mucinous adenoma (... -1.100 0.000
lung cancer -2.100 0.012
colon cancer -1.400 0.041
breast carcinoma -1.200 0.000
pediatric high grade glioma -4.500 0.000
pilocytic astrocytoma -2.200 0.000
non primary Sjogren syndrome sicca 1.100 0.021
pancreatic carcinoma 1.600 0.000
lung adenocarcinoma -1.300 0.000
Breast cancer -1.700 0.000
non-small cell lung carcinoma -1.100 0.000
Pick disease -1.900 0.004
invasive ductal carcinoma -1.100 0.043
ovarian cancer -4.000 0.000
head and neck cancer and chronic obstruc... -1.200 0.003

Synonym

Accession P37840 A8K2A4 Q13701 Q4JHI3 Q6IAU6
Symbols PD1
NACP
PARK1
PARK4

Gene

PANTHER Protein Class (1)