MPG
DNA-3-methyladenine glycosylase
Protein Summary
Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.
- ENST00000219431
- ENSP00000219431
- ENSG00000103152
- ENST00000356432
- ENSP00000348809
- ENST00000397817
- ENSP00000380918
- AAG
- ANPG
- MID1
- AAG
- MDG
- ADPG
- APNG
- Mid1
- anpg
- PIG11
- PIG16
- CRA36.1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
disease perturbation | 0.93 | ||
interacting protein | 0.82 | ||
transcription factor binding site profile | 0.68 | ||
molecular function | 0.67 | ||
kinase perturbation | 0.66 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 360.25 (req: < 5)
Gene RIFs: 54 (req: <= 3)
Antibodies: 389 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 360.25 (req: >= 5)
Gene RIFs: 54 (req: > 3)
Antibodies: 389 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 10
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 1
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0