Property Summary

NCBI Gene PubMed Count 71
Grant Count 8
R01 Count 3
Funding $275,790.83
PubMed Score 49.67
PubTator Score 82.25

Knowledge Summary

Patent (4,592)

Expression

  Differential Expression (6)

Disease log2 FC p
astrocytic glioma 1.100 0.019
ependymoma 1.500 0.013
oligodendroglioma 1.700 0.001
osteosarcoma 1.696 0.000
group 4 medulloblastoma 1.100 0.040
subependymal giant cell astrocytoma -1.383 0.033

Synonym

Accession P28702 P28703 Q59G65 Q5JP92 Q5STQ1
Symbols NR2B2
DAUDI6
RCoR-1
H-2RIIBP

Gene

PDB

1H9U   1UHL   5HJP   5I4V   5KYA   5KYJ  

  TechDev Info (1)

Jun Qin Signaling network evaluation of transcript factor crosstalk via catTRE/MS

Gene RIF (32)

PMID Text
26355550 Data show that pregnane X receptor/retinoid X receptor PXR/RXR-[alpha], RXR-[beta], or RXR-[gamma] expression was noted in 9 (16.4%), 9 (16.4%), and 10 (18.2%) pancreatic adenocarcinoma cases, respectively.
24183235 RXR interaction is necessary for NPM-RAR-mediated myeloid maturation arrest.
22322885 A fatty acid-binding protein 7/RXRbeta pathway enhances survival and proliferation in triple-negative breast cancer.
21923909 HIV-1 Nef induces loss of F-actin assembly and inhibits retinoid receptor-mediated transcription
20628086 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
20587610 Observational study of gene-disease association. (HuGE Navigator)
19913121 Observational study of gene-disease association. (HuGE Navigator)
19888660 Observational study of gene-disease association. (HuGE Navigator)
19851445 Observational study of gene-disease association. (HuGE Navigator)
19811264 Observational study of gene-disease association. (HuGE Navigator)
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AA Sequence

MSWAARPPFLPQRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAVAGGEQQTPEPEPGEAGR      1 - 70
DGMGDSGRDSRSPDSSSPNPLPQGVPPPSPPGPPLPPSTAPSLGGSGAPPPPPMPPPPLGSPFPVISSSM     71 - 140
GSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRGLHCPPPPGGPGAGKRLCAICGD    141 - 210
RSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQ    211 - 280
RGKDKDGDGEGAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTL    281 - 350
VEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRV    351 - 420
LTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYPEQQGRFAKLL    421 - 490
LRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA                               491 - 533
//

Text Mined References (75)

PMID Year Title
26871637 2016 Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
26355550 2015 Pregnane X Receptor Expression in Human Pancreatic Adenocarcinoma: Associations With Clinicopathologic Parameters, Tumor Proliferative Capacity, Patients' Survival, and Retinoid X Receptor Expression.
25303530 2014 Enhancer activation requires trans-recruitment of a mega transcription factor complex.
24275569 2014 An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
24183235 2013 Interaction with RXR is necessary for NPM-RAR-induced myeloid differentiation blockade.
24129315 2014 Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
23740775 2013 Association of granulomatosis with polyangiitis (Wegener's) with HLA-DPB1*04 and SEMA6A gene variants: evidence from genome-wide analysis.
22322885 2012 A fatty acid-binding protein 7/RXR? pathway enhances survival and proliferation in triple-negative breast cancer.
21988832 2011 Toward an understanding of the protein interaction network of the human liver.
20628086 2010 Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
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