Tbio MZF1 Myeloid zinc finger 1

Protein Summary

Description

Binds to target promoter DNA and functions as transcription regulator. Regulates transcription from the PADI1 and CDH2 promoter. May be one regulator of transcriptional events during hemopoietic development.

Uniprot Accession IDs

• P28698
• M0QXU0
• Q7Z729
• Q96I71
• Q9NRY0
• Q9UBW2
• MZF-1

Gene Name

• MZF1

Ensembl ID

• ENST00000215057
• ENSP00000215057
• ENSG00000099326
• ENST00000594234
• ENSP00000469378
• ENST00000599369
• ENSP00000469493

Symbol

• MZF
• ZNF42
• ZSCAN6
• MZF-1
• MZF1B
• ZFP98
• ZNF42
• ZSCAN6

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.94
transcription factor binding site profile	0.8
disease perturbation	0.79
protein domain	0.73
biological process	0.62

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 88.58   (req: < 5)

Gene RIFs: 38   (req: <= 3)

Antibodies: 140   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 88.58   (req: >= 5)

Gene RIFs: 38   (req: > 3)

Antibodies: 140   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 11

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0