Property Summary

NCBI Gene PubMed Count 1,189
Grant Count 1,718
R01 Count 1,111
Funding $133,810,799.89
PubMed Score 5447.09
PubTator Score 4570.69

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Relevance (67)

Disease Z-score Confidence
Cancer 2,346 7.551 3.8
Adenoma 165 4.615 2.3
ductal carcinoma in situ 1,745 3.708 1.9
Gastrointestinal system disease 50 3.413 1.7
Vascular disease 281 3.305 1.7
Parathyroid Adenoma 11 3.271 1.6
Familial adenomatous polyposis 31 3.221 1.6
Intestinal benign neoplasm 11 3.193 1.6
Primary hyperparathyroidism 4 3.043 1.5
Papilloma 27 3.037 1.5
Adenoid Cystic Carcinoma 99
Animal Mammary Neoplasms 136
Brain Neoplasms 23
Breast cancer 3,094 2.0
Carcinoma, Transitional Cell 31
Cecal Neoplasms 4
Chronic Lymphocytic Leukemia 242
Colonic Neoplasms 126
Colorectal Neoplasms 217
Esophageal Neoplasms 67
Hemangiosarcoma 18
Hormone receptor positive malignant neop... 10 
Human epidermal growth factor 2 negative... 3 
Hydrolethalus syndrome 128
Hyperparathyroidism 43
Hyperplasia 26
Intestinal Polyps 5
Kidney Neoplasm 27
Kidney cancer 118 1.0
Leukemia 88
Liver carcinoma 217
Lung Neoplasms 171
Malignant lymphoma, lymphocytic, interme... 12 
Mammary Neoplasms 410
Mammary Neoplasms, Experimental 150
Multiple myeloma 1,327
Myocardial Ischemia 169
Neoplasms, Experimental 33
Neoplastic Cell Transformation 81
Precancerous Conditions 69
Prostatic Neoplasms 471
Salivary Gland Neoplasms 45
Squamous cell carcinoma of esophagus 82
Stomach Neoplasms 282
Thyroid Neoplasm 33
Urologic Neoplasms 7
Von Hippel-Lindau Syndrome 2
astrocytoma 1,493
atypical teratoid/rhabdoid tumor 1,095
colon cancer 1,475
cystic fibrosis 1,665
ependymoma 2,514
glioblastoma 5,572
group 4 medulloblastoma 1,875
lung cancer 4,466
malignant mesothelioma 3,162
medulloblastoma, large-cell 6,234
nasopharyngeal carcinoma 1,056
oligodendroglioma 2,849
osteosarcoma 7,933
ovarian cancer 8,484
pediatric high grade glioma 2,712
pilocytic astrocytoma 3,086
pituitary cancer 1,972
primitive neuroectodermal tumor 3,031
psoriasis 6,685
subependymal giant cell astrocytoma 2,287

Expression

  Differential Expression (21)

Disease log2 FC p
malignant mesothelioma -1.600 0.000
psoriasis -1.500 0.000
astrocytoma 1.200 0.000
oligodendroglioma 1.300 0.000
osteosarcoma 2.559 0.004
ependymoma 2.500 0.000
glioblastoma 2.300 0.001
cystic fibrosis 1.148 0.000
atypical teratoid/rhabdoid tumor 2.400 0.000
medulloblastoma, large-cell -1.100 0.002
primitive neuroectodermal tumor 2.000 0.020
Hydrolethalus syndrome 1.674 0.037
lung cancer 1.300 0.001
colon cancer 1.700 0.000
pediatric high grade glioma 2.300 0.000
group 4 medulloblastoma -1.700 0.000
pilocytic astrocytoma 2.700 0.000
subependymal giant cell astrocytoma 1.432 0.015
Breast cancer 1.100 0.004
ovarian cancer 3.300 0.000
pituitary cancer 1.100 0.000

Synonym

Accession P24385 Q6LEF0
Symbols BCL1
PRAD1
U21B31
D11S287E

Gene

PDB

2W96   2W99   2W9F   2W9Z