CPT2
Carnitine O-palmitoyltransferase 2, mitochondrial
Protein Summary
The protein encoded by this gene is a nuclear protein which is transported to the mitochondrial inner membrane. Together with carnitine palmitoyltransferase I, the encoded protein oxidizes long-chain fatty acids in the mitochondria. Defects in this gene are associated with mitochondrial long-chain fatty-acid (LCFA) oxidation disorders. [provided by RefSeq, Jul 2008]
- ENST00000371486
- ENSP00000360541
- ENSG00000157184
- CPT1
- CPT1
- IIAE4
- CPTASE
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
metabolite | 1 | ||
phenotype | 0.77 | ||
cellular component | 0.72 | ||
interacting protein | 0.72 | ||
kinase perturbation | 0.71 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 361.86 (req: < 5)
Gene RIFs: 61 (req: <= 3)
Antibodies: 454 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 361.86 (req: >= 5)
Gene RIFs: 61 (req: > 3)
Antibodies: 454 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 5
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligands: 35
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0