Tbio F8A1 Factor VIII intron 22 protein

Protein Summary

Description

Not known. Possible housekeeping role. This gene is part of a region that is repeated three times on chromosome X, once in intron 22 of the F8 gene and twice closer to the Xq telomere. This record represents the middle copy. Although its function is unknown, the observation that this gene is conserved in the mouse implies it has some function. Unlike factor VIII, this gene is transcribed abundantly in a wide variety of cell types. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• P23610
• Q5HY66
• Q8IXP3

Gene Name

• F8A1

Ensembl ID

• ENST00000369505
• ENSP00000358518
• ENSG00000274791
• ENST00000610495
• ENSP00000479624
• ENSG00000277203
• ENST00000622749
• ENSP00000477530
• ENSG00000277150

Symbol

• F8A

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
tissue sample	0.62
microRNA	0.5
co-expressed gene	0.48
transcription factor	0.43
cell line	0.39

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 53.88   (req: < 5)

Gene RIFs: 12   (req: <= 3)

Antibodies: 61   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 53.88   (req: >= 5)

Gene RIFs: 12   (req: > 3)

Antibodies: 61   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0