Tclin CA6 Carbonic anhydrase 6

Protein Summary

Description

Reversible hydration of carbon dioxide. Its role in saliva is unknown. The protein encoded by this gene is one of several isozymes of carbonic anhydrase. This protein is found only in salivary glands and saliva and protein may play a role in the reversible hydratation of carbon dioxide though its function in saliva is unknown. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• P23280
• E7EMQ1
• Q5FBW3
• Q5FC00
• Q96QX8
• Q9UF03

Gene Name

• CA6

Ensembl ID

• ENST00000377436
• ENSP00000366654
• ENSG00000131686
• ENST00000377442
• ENSP00000366661
• ENST00000377443
• ENSP00000366662

Symbol

• CA-VI
• GUSTIN

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
gene perturbation	0.91
protein domain	0.58
hub protein	0.53
cell line	0.5
cellular component	0.47

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 420.14   (req: < 5)

Gene RIFs: 27   (req: <= 3)

Antibodies: 331   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 420.14   (req: >= 5)

Gene RIFs: 27   (req: > 3)

Antibodies: 331   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 222

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drugs: 15