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Tbio
ZNF24
Zinc finger protein 24

Protein Summary
Description
Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5'-TCAT-3' DNA sequence (By similarity). Has transcription repressor activity in vitro.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000261332
  • ENSP00000261332
  • ENSG00000172466
  • ENST00000399061
  • ENSP00000382015
  • ENST00000589881
  • ENSP00000467655

Symbol
  • KOX17
  • ZNF191
  • ZSCAN3
  • KOX17
  • RSG-A
  • ZNF191
  • ZSCAN3
  • Zfp191
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.96
disease perturbation
0.93
virus perturbation
0.92
microRNA
0.86
histone modification site profile
0.84


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 39.52   (req: < 5)
Gene RIFs: 13   (req: <= 3)
Antibodies: 235   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 39.52   (req: >= 5)
Gene RIFs: 13   (req: > 3)
Antibodies: 235   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0