Property Summary

NCBI Gene PubMed Count 904
Grant Count 1,635
R01 Count 959
Funding $186,657,082.72
PubMed Score 6460.00
PubTator Score 3956.57

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Relevance (63)

Disease Z-score Confidence
Cancer 2,346 6.926 3.5
Arthritis 248 4.165 2.1
Kidney disease 396 3.774 1.9
Hypersensitivity reaction type II diseas... 235  3.772 1.9
Vascular disease 281 3.404 1.7
Adenoma 165 3.4 1.7
Inflammatory bowel disease 142 3.248 1.6
Lymphopenia 35 3.184 1.6
Severe Combined Immunodeficiency 46 3.094 1.5
Acute Promyelocytic Leukemia 31
Acute kidney injury 65
Arsenic Poisoning 59
Becker muscular dystrophy 187
COPD 113
Contact Dermatitis 80
Dermatologic disorders 65
Down syndrome 548
Duchenne muscular dystrophy 602
IGA Glomerulonephritis 454
Leukemia, Myelocytic, Acute 113
Mammary Neoplasms, Experimental 150
Neoplasm Metastasis 138
Nerve Degeneration 73
Pancreatic Neoplasm 79
Peripheral Neuropathy 303
Rheumatoid Arthritis 1,160
Stomach Neoplasms 282
Vitiligo 71
Waldenstrons macroglobulinemia 765
active Crohn's disease 918
acute quadriplegic myopathy 1,157
adrenocortical carcinoma 1,427
astrocytic glioma 2,241
atypical teratoid / rhabdoid tumor 4,369
autosomal dominant Emery-Dreifuss muscul... 499 
colon cancer 1,475
dermatomyositis 933
diabetes mellitus 1,663
ductal carcinoma in situ 1,745
ependymoma 2,514
fascioscapulohumeral muscular dystrophy 100
gastric carcinoma 832
glioblastoma 5,572
intraductal papillary-mucinous adenoma (... 2,956 
invasive ductal carcinoma 2,950
juvenile dermatomyositis 1,189
limb girdle muscular dystrophy 2I 56
lung cancer 4,466
malignant mesothelioma 3,162
nephrosclerosis 329
non diabetic and post-ischemic heart fai... 200 
non primary Sjogren syndrome sicca 840
oligodendroglioma 2,849
ovarian cancer 8,484
pancreatic ductal adenocarcinoma liver m... 1,795 
pediatric high grade glioma 2,712
pilocytic astrocytoma 3,086
pituitary cancer 1,972
psoriasis 6,685
subependymal giant cell astrocytoma 2,287
tuberculosis 1,557
ulcerative colitis 2,087
uncontrolled asthma 67

Expression

Gene

PDB

1POZ   1UUH   2I83   4PZ3   4PZ4