Protein Summary
Appears to have a function in striated muscle development and regeneration. This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme is found in skeletal muscle cells in the adult where it may play a role in muscle development and regeneration. A switch from alpha enolase to beta enolase occurs in muscle tissue during development in rodents. Mutations in this gene have be associated glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Jul 2010]
- ENST00000323997
- ENSP00000324105
- ENSG00000108515
- ENST00000518175
- ENSP00000431087
- ENST00000519584
- ENSP00000430636
- MSE
- GSD13
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
PubMedID | 0.87 | ||
protein domain | 0.85 | ||
disease perturbation | 0.83 | ||
transcription factor | 0.79 | ||
gene perturbation | 0.77 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 361.29 (req: < 5)
Gene RIFs: 6 (req: <= 3)
Antibodies: 353 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 361.29 (req: >= 5)
Gene RIFs: 6 (req: > 3)
Antibodies: 353 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 9
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0