Property Summary

Ligand Count 22
NCBI Gene PubMed Count 1,217
PubMed Score 7088.31
PubTator Score 4030.37

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (6)

Disease Target Count Z-score Confidence
Atherosclerosis 291 6.458 3.2
Coronary artery disease 268 4.999 2.5
Hypertension 396 4.733 2.4
Asthma 385 4.528 2.3
Brain Injuries 65 0.0 0.0
Brain Ischemia 110 0.0 0.0
Bronchial Hyperreactivity 12 0.0 0.0
Calcinosis 70 0.0 0.0
Carcinoma, Squamous Cell 110 0.0 0.0
Cardiovascular Diseases 59 0.0 0.0
Carotid Artery Diseases 11 0.0 0.0
Chemical and Drug Induced Liver Injury 195 0.0 0.0
Crohn Disease 45 0.0 0.0
Diabetic Nephropathies 37 0.0 0.0
Endometrial Neoplasms 55 0.0 0.0
Glomerulonephritis 46 0.0 0.0
HIV Infections 102 0.0 0.0
Heart Valve Diseases 25 0.0 0.0
Hepatitis, Autoimmune 17 0.0 0.0
Hyperalgesia 83 0.0 0.0
Hyperoxaluria 8 0.0 0.0
Hypersensitivity 63 0.0 0.0
Hypertension, Pulmonary 37 0.0 0.0
Infarction, Middle Cerebral Artery 33 0.0 0.0
Inflammation 120 0.0 0.0
Influenza, Human 51 0.0 0.0
Kidney Failure, Chronic 46 0.0 0.0
Leishmaniasis, Cutaneous 8 0.0 0.0
Liver Cirrhosis 181 0.0 0.0
Liver Cirrhosis, Experimental 769 0.0 0.0
Liver diseases 87 0.0 0.0
Lung Injury 20 0.0 0.0
MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO 11 0.0 0.0
Metabolic Syndrome 20 0.0 0.0
Mouth Neoplasms 55 0.0 0.0
Multiple myeloma 1332 0.0 0.0
Muscular Dystrophy, Duchenne 7 0.0 0.0
Myocardial Ischemia 169 0.0 0.0
Myocardial Reperfusion Injury 37 0.0 0.0
Neoplasm Invasiveness 161 0.0 0.0
Nephritis, Interstitial 10 0.0 0.0
Neural Tube Defects 31 0.0 0.0
Obstetric Labor, Premature 2 0.0 0.0
Pleural Diseases 10 0.0 0.0
Pneumonia 174 0.0 0.0
Pulmonary Fibrosis 106 0.0 0.0
Reperfusion Injury 86 0.0 0.0
Respiratory Distress Syndrome, Adult 40 0.0 0.0
Retinal Degeneration 106 0.0 0.0
Schizophrenia 1160 0.0 0.0
Silicosis 12 0.0 0.0
Spinal Cord Compression 3 0.0 0.0
Spinal Dysraphism 12 0.0 0.0
Status Epilepticus 98 0.0 0.0
Thyroid Diseases 24 0.0 0.0
Thyroid Neoplasms 34 0.0 0.0
Tuberculosis, Pulmonary 3 0.0 0.0
Disease Target Count Z-score Confidence
Crohn's disease 321 0.0 1.4

Expression

  Differential Expression (31)

Disease log2 FC p
tuberculosis -4.500 4.1e-04
psoriasis 1.400 4.8e-04
adrenocortical adenoma -2.188 1.8e-03
adrenocortical carcinoma -3.639 2.5e-06
adult high grade glioma 2.800 8.4e-05
Astrocytoma, Pilocytic 3.300 1.4e-09
Atopic dermatitis 1.300 7.6e-03
atypical teratoid / rhabdoid tumor 3.000 1.2e-03
autosomal dominant Emery-Dreifuss muscul... 1.109 2.5e-02
cutaneous lupus erythematosus 2.300 2.3e-03
cystic fibrosis 2.552 4.3e-06
ependymoma 3.200 2.5e-06
Gaucher disease type 3 -1.700 2.5e-02
glioblastoma 1.900 8.7e-03
head and neck cancer 1.800 3.7e-02
interstitial cystitis 1.800 9.5e-03
intraductal papillary-mucinous adenoma (... -2.300 5.8e-03
intraductal papillary-mucinous carcinoma... -2.500 5.2e-03
intraductal papillary-mucinous neoplasm ... -2.300 4.1e-02
invasive ductal carcinoma -2.480 1.9e-04
juvenile dermatomyositis 1.446 4.6e-07
lung adenocarcinoma -1.222 5.3e-03
lung cancer -2.700 9.5e-06
lung carcinoma -2.700 2.2e-10
nasopharyngeal carcinoma 2.000 2.4e-03
non diabetic and post-ischemic heart fai... -2.000 2.0e-02
non-small cell lung cancer -2.264 1.3e-10
ovarian cancer 1.500 5.6e-03
pituitary cancer -2.400 1.8e-04
Systemic lupus erythematosus 1.100 1.9e-02
ulcerative colitis 2.800 3.1e-04

Gene RIF (1317)

AA Sequence

MKVSAALLCLLLIAATFIPQGLAQPDAINAPVTCCYNFTNRKISVQRLASYRRITSSKCPKEAVIFKTIV      1 - 70
AKEICADPKQKWVQDSMDHLDKQTQTPKT                                              71 - 99
//

Text Mined References (1221)

PMID Year Title