Property Summary

NCBI Gene PubMed Count 2,328
Grant Count 3,200
R01 Count 1,280
Funding $1,050,184,431.88
PubMed Score 29360.39
PubTator Score 16082.84

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Relevance (109)

Disease Z-score Confidence
Hypertension 287 8.438 4.0
Coronary artery disease 240 7.605 3.8
Kidney disease 396 7.485 3.7
Heart disease 279 7.46 3.7
sarcoidosis 358 7.021 3.5
diabetes mellitus 1,663 6.955 3.5
Angioedema 36 6.553 3.3
Cerebrovascular disease 231 6.454 3.2
Atherosclerosis 275 5.574 2.8
Lung disease 132 5.348 2.7
Lipid metabolism disorder 102 4.773 2.4
Obesity 616 4.584 2.3
Anemia 252 4.414 2.2
Metabolic syndrome X 155 4.372 2.2
Dementia 129 4.342 2.2
Peripheral vascular disease 90 4.259 2.1
Hyperglycemia 120 4.232 2.1
Connective tissue disease 59 4.162 2.1
Hypersensitivity reaction type II diseas... 235  4.117 2.1
Diabetic Retinopathy 53 4.109 2.1
Uveitis 103 4.089 2.0
Renal artery disease 3 4.059 2.0
Cancer 2,346 4.048 2.0
Hypokalemia 40 3.833 1.9
Alzheimer's disease 644 3.818 1.9
Asthma 349 3.802 1.9
Oligohydramnios 18 3.773 1.9
Polycystic kidney disease 54 3.695 1.8
Impotence 45 3.682 1.8
Intermittent claudication 16 3.66 1.8
Hyperaldosteronism 27 3.605 1.8
Peripheral artery disease 8 3.544 1.8
Neuropathy 210 3.499 1.7
Exanthem 39 3.49 1.7
Transient cerebral ischemia 14 3.443 1.7
Liver disease 219 3.422 1.7
Allergic hypersensitivity disease 123 3.42 1.7
Conn's syndrome 22 3.419 1.7
C1 inhibitor deficiency 9 3.407 1.7
Gaucher's disease 24 3.406 1.7
Urticaria 53 3.349 1.7
Aortic aneurysm 34 3.338 1.7
Migraine 79 3.242 1.6
tuberculosis 1,557 3.166 1.6
Hyperinsulinism 63 3.153 1.6
Vasculitis 64 3.133 1.6
Hypertensive encephalopathy 3 3.114 1.6
Lymphatic system disease 14 3.017 1.5
Alport syndrome 21 3.013 1.5
ANGIOTENSIN I-CONVERTING ENZYME, BENIGN ... 1 
Adenocarcinoma 115
Albuminuria 20
Allanson Pantzar McLeod syndrome 4
Asymptomatic left ventricular systolic d... 1 
Atrial Fibrillation 110
Berylliosis 16
Brain Ischemia 87
Cardiac Arrhythmia 20
Cardiovascular Diseases 50
Cerebral Hemorrhage 27
Cerebrovascular accident 44
Chronic heart failure 46
Congestive heart failure 30
Coronary Restenosis 8
Coronary heart disease 59
Coughing 2
Diabetes Mellitus, Experimental 106
Diabetic Nephropathy 37
Diabetic renal disease 4
Drug allergy 36
Gaucher Disease 4
Glycogen Storage Disease Type V 2
Heart failure 80
Hypertensive disease 193
Hypertensive disorder 58
Hypotension 53
IGA Glomerulonephritis 454
IgA NEPHROPATHY, PROGRESSION TO RENAL FA... 2 
Infant, Premature, Diseases 1
Kidney Diseases 86
Kidney Failure, Chronic 45
Left Ventricular Hypertrophy 24
Left ventricular cardiac dysfunction 9
Liver carcinoma 217
Lung Neoplasms 171
Lung diseases 48
MICROVASCULAR COMPLICATIONS OF DIABETES,... 2 
MICROVASCULAR COMPLICATIONS OF DIABETES,... 1 
Male infertility 170
Meningococcal Infections 4
Myocardial Infarction 126
Myocardial Infarction Prevention 7
Neoplasm Metastasis 138
Non-alcoholic Fatty Liver Disease 40
Pneumonia, Viral 1
Prostatic Neoplasms 471
Psychoses, Substance-Induced 17
Pulmonary hypertension 52
Renal Insufficiency 10
Respiratory Tract Diseases 6
Severe acute respiratory syndrome 26
Staphylococcal Infections 4
Stomach Neoplasms 282
Sudden death 2
Superficial Ocular Infection 6
facioscapulohumeral dystrophy 286
lung adenocarcinoma 2,713
non-small cell lung cancer 2,798
pre-eclampsia 67

Expression

  Differential Expression (3)

Disease log2 FC p
non-small cell lung cancer -1.692 0.000
lung adenocarcinoma -1.500 0.000
facioscapulohumeral dystrophy 1.800 0.040

Synonym

Accession P12821 B0LPF0 B4DXI3 E7EU16 P22966 Q53YX9 Q59GY8 Q7M4L4 ACE
Symbols DCP
ACE1
DCP1
CD143

Gene

ACE