Property Summary

NCBI Gene PubMed Count 108
Grant Count 257
R01 Count 173
Funding $19,251,403.63
PubMed Score 1229.84
PubTator Score 777.73

Knowledge Summary

Patent

No data available

Expression

Synonym

Accession P10082 Q5U5Q6 Q6FGH8 PYY
Symbols PYY1
PYY-I

Gene

PYY

PDB

2DEZ   2DF0   2L60  

Gene RIF (97)

PMID Text
26762368 Data suggest that endocrine responses differ between jejunal and gastric enteral feeding, with higher peak plasma CCK (cholecystokinin), PYY (peptide YY), and GLP-1/2 (glucagon-like peptides 1/2) concentrations being attained after jejunal feeding.
26718419 Data suggest that capsaicin, an appetite suppressant dietary supplement (here, administered via intraduodenal infusion), does not act via alteration of secretion of satiety hormones PYY (peptide YY) and GLP-1 (GLP-1).
26506614 In male GERD patients, EE was associated with significantly higher PYY levels [107.0 (55.0-120.8) vs. 32.8 (28.7-84.5) pg/ml, p = 0.026] but lower adiponectin levels [6.7 (5.6-9.3) vs. 9.9 (9.6-10.6) mug/ml, p = 0.034] than NE
26002416 Immunohistochemical distribution of this peptide in the epidermal skin (from abdomen, breast and face) of healthy women was analysed.
25990478 Plasma PYY and PP levels were significantly higher in HG [Hyperemesis gravidarum ] group.
25823991 Data suggest plasma PYY (peptide YY) and GLP1 (glucagon-like peptide 1) can be regulated by digestion-resistant diet factors; intake of soluble dietary fiber (prebiotic Fibersol-2) in a tea with meal up-regulated plasma PYY/GLP1 and decreased hunger.
25661189 Data suggest secretion of PYY and GLP1 (glucagon-like peptide-1) can be altered by diet; plasma levels of PYY/GLP1 are increased during postprandial period after meal using Paleolithic diet principles (high in protein/plant matter; no cereals/dairy).
25568079 Intraduodenal lipid more potently stimulated PYY release when compared to intraduodenal protein.
25494974 Data suggest that, despite effects of acute sprint interval exercise (SIE) on oxygen consumption, appetite regulation, and brief up-regulation of plasma PYY, acute SIE does not affect energy intake of young men.
25361054 Eating speed at breakfast did not affect postprandial ghrelin, GLP-1, PYY, hunger, and fullness values or daily energy and macronutrient intake.
More...

AA Sequence

MVFVRRPWPALTTVLLALLVCLGALVDAYPIKPEAPREDASPEELNRYYASLRHYLNLVTRQRYGKRDGP      1 - 70
DTLLSKTFFPDGEDRPVRSRSEGPDLW                                                71 - 97
//

Text Mined References (110)

PMID Year Title
26762368 2016 Jejunal feeding is followed by a greater rise in plasma cholecystokinin, peptide YY, glucagon-like peptide 1, and glucagon-like peptide 2 concentrations compared with gastric feeding in vivo in humans: a randomized trial.
26718419 2016 Capsaicin-induced satiety is associated with gastrointestinal distress but not with the release of satiety hormones.
26506614 2015 Associations of Circulating Gut Hormone and Adipocytokine Levels with the Spectrum of Gastroesophageal Reflux Disease.
26002416 2015 Immunohistochemical distribution of neuropeptide Y, peptide YY, pancreatic polypeptide-like immunoreactivity and their receptors in the epidermal skin of healthy women.
25990478 2015 Gut satiety hormones and hyperemesis gravidarum.
25823991 2015 Soluble dietary fiber (Fibersol-2) decreased hunger and increased satiety hormones in humans when ingested with a meal.
25661189 2015 Plant-rich mixed meals based on Palaeolithic diet principles have a dramatic impact on incretin, peptide YY and satiety response, but show little effect on glucose and insulin homeostasis: an acute-effects randomised study.
25568079 2015 Comparative effects of intraduodenal protein and lipid on ghrelin, peptide YY, and leptin release in healthy men.
25494974 2015 Energy intake over 2 days is unaffected by acute sprint interval exercise despite increased appetite and energy expenditure.
25361054 2015 The effect of eating speed at breakfast on appetite hormone responses and daily food consumption.
More...