Tdark | Olfactory receptor 5H8 |
Odorant receptor.
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Comments
MDDENATLLTEFVLTGLTYQSEWKIPLFLAFLVIYLITIMANLGLIAVIWKDSHLHIPMYLFLGSLAFVD 1 - 70 AWLSSSVTPKMLISFLAKSMIISVSECKIQFFSFGISGTTECFLLATMAYDRYVAICKPLLYPVIMTNGL 71 - 140 CIWLLVLSFIGGFLHALIHEGILFRLTFCNSNIIHHFYCDIIPLLKISCTDPSINFLMLFILSGSIQVFT 141 - 210 ILTVLVSYTFVLFTILKKKAKDIRKAFSTCGAHLLSVSLYYGPLLFMYVHPASPQADDQDMVESLFYTVI 211 - 280 IPFLNPIIYSLRNKQVIDSLTKTLKGNV 281 - 308 //
PMID | Year | Title |
---|---|---|
22908908 | 2012 | Personal receptor repertoires: olfaction as a model. |
16641997 | 2006 | The DNA sequence, annotation and analysis of human chromosome 3. |
14983052 | 2004 | The human olfactory receptor gene family. |
12908129 | 2003 | Natural selection on the olfactory receptor gene family in humans and chimpanzees. |