Property Summary

NCBI Gene PubMed Count 86
Grant Count 5
Funding $1,097,392
PubMed Score 87.13
PubTator Score 87.43

Knowledge Summary

Patent

No data available

Expression

Gene RIF (2)

PMID Text
24284944 Pepsin and pepsinogen in middle ear effusion are probably caused by LPR and may be involved in the pathogenesis of OME.
23311720 Levels of pepsinogen/pepsin A and C are higher in the mouth swabs of preterm infants with gastroesophageal reflux.

AA Sequence

MKWLLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLVDEQPLEN      1 - 70
YLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNPEDSSTYQSTSETVSITYGTG     71 - 140
SMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGATPVFDNIWNQGLVSQ    141 - 210
DLFSVYLSADDKSGSVVIFGGIDSSYYTGSLNWVPVTVEGYWQITVDSITMNGETIACAEGCQAIVDTGT    211 - 280
SLLTGPTSPIANIQSDIGASENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQSEGSCISGFQG    281 - 350
MNVPTESGELWILGDVFIRQYFTVFDRANNQVGLAPVA                                    351 - 388
//

Text Mined References (88)

PMID Year Title
25314140 2014 Prediction of gastric cancer development by serum pepsinogen test and Helicobacter pylori seropositivity in Eastern Asians: a systematic review and meta-analysis.
24383519 2014 The value of serum pepsinogen levels for the diagnosis of gastric diseases in Chinese Han people in midsouth China.
24284944 2014 Role of pepsin and pepsinogen: linking laryngopharyngeal reflux with otitis media with effusion in children.
24170207 2014 Serum pepsinogen reference intervals in apparently healthy Chinese population with latex enhanced turbidimetric immunoassay.
24125879 2014 A possible association of low pepsinogen I and pepsinogen I/II with low and high body weight in Japanese men.
24004680 2013 Pepsinogen I and II expressions in situ and their correlations with serum pesignogen levels in gastric cancer and its precancerous disease.
23897256 2013 Gastric cancer detection using gastric juice pepsinogen and melanoma-associated gene RNA.
23533145 2013 In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.
23521833 2013 Expression of serum miR-20a-5p, let-7a, and miR-320a and their correlations with pepsinogen in atrophic gastritis and gastric cancer: a case-control study.
23311720 2013 Detection of pepsin in mouth swab: correlation with clinical gastroesophageal reflux in preterm infants.
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