Property Summary

NCBI Gene PubMed Count 9
PubMed Score 0.00

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Relevance (1)

Disease Z-score Confidence
diabetes mellitus 1,663

Gene RIF (1)

PMID Text
23402768 Data suggest that humanin (the first small peptide of a putative set of mitochondrial derived peptides) exhibits strong cytoprotective actions against various stress and disease models.

AA Sequence

MTTRGFSCLLLLIREIDLSAKRRI                                                    1 - 24
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Text Mined References (9)

PMID Year Title
25630734 2016 The human mitochondrial genome may code for more than 13 proteins.
23402768 2013 Humanin: a harbinger of mitochondrial-derived peptides?
20542501 2010 Immunolocalization of humanin in human sperm and testis.
19623253 2009 Humanin: a novel central regulator of peripheral insulin action.
19477263 2009 Evidence for potential functionality of nuclearly-encoded humanin isoforms.
15772651 2005 The DNA sequence of the human X chromosome.
12732850 2003 Humanin peptide suppresses apoptosis by interfering with Bax activation.
12009529 2002 Evidence for in vivo production of Humanin peptide, a neuroprotective factor against Alzheimer's disease-related insults.
11371646 2001 A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Abeta.