Tdark UBTFL1 Upstream-binding factor 1-like protein 1

Protein Summary

Description

Essential for proliferation of the inner cell mass and trophectodermal cells in peri-implantation development. UBTFL1 is a preimplantation-specific gene and is involved in early development, implantation, and embryonic stem (ES) cell derivation (summary by Yamada et al., 2010 [PubMed 19915186]).[supplied by OMIM, Jan 2011]

Uniprot Accession IDs

• P0CB47
• C9JMX8

Gene Name

• UBTFL1

Ensembl ID

• ENST00000530464
• ENSP00000485108
• ENSG00000255009

Symbol

• C11orf27
• HMGPI
• C11orf27

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
PubMedID	0.84
cell line	0.73
protein complex	0.4
cellular component	0.34
biological term	0.33

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.64   (req: < 5)

Gene RIFs: 1   (req: <= 3)

Antibodies: 22   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.64   (req: >= 5)

Gene RIFs: 1   (req: > 3)

Antibodies: 22   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0