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Tclin
TACSTD2
Tumor-associated calcium signal transducer 2

Protein Summary
Description
May function as a growth factor receptor. This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.[provided by RefSeq, Dec 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000371225
  • ENSP00000360269
  • ENSG00000184292

Symbol
  • GA733-1
  • M1S1
  • TROP2
  • EGP1
  • GP50
  • M1S1
  • EGP-1
  • TROP2
  • GA7331
  • GA733-1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
PubMedID
1
gene perturbation
0.91
virus perturbation
0.85
transcription factor perturbation
0.74
cellular component
0.71


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 566.49   (req: < 5)
Gene RIFs: 127   (req: <= 3)
Antibodies: 546   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 566.49   (req: >= 5)
Gene RIFs: 127   (req: > 3)
Antibodies: 546   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 14
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 1