Property Summary

NCBI Gene PubMed Count 21
PubMed Score 0.78
PubTator Score 40.88

Knowledge Summary


No data available



Accession P09132 B2R4E9 D6RCQ5 Q05D77 Q96FG6 SRP19



4P3E   1RY1   1MFQ   1JID   2J37   3KTV  

  Ortholog (11)

Species Source
Chimp OMA EggNOG
Macaque OMA EggNOG Inparanoid
Mouse OMA EggNOG Inparanoid
Rat OMA EggNOG Inparanoid
Cow OMA EggNOG Inparanoid
Opossum OMA EggNOG Inparanoid
Platypus OMA EggNOG
Chicken OMA EggNOG Inparanoid
Anole lizard OMA EggNOG Inparanoid
Xenopus OMA EggNOG Inparanoid
C. elegans OMA EggNOG Inparanoid

Gene RIF (6)

20179341 crystal structures of a crenarchaeal and the all-human SRP19-signal recognition particle RNA binary complexes presented here show that the asymmetric loop is bulged out in both binary complexes.
17881443 Overexpression of SRP19 reduces the HIV-1 NC-mediated packaging of 7SL RNA and A3G into virions in a dose-dependent manner
17434535 Data show that the presence of SRP54 during SRP19-RNA assembly dramatically alters the folding energy landscape to create a non-native folding pathway that leads to an aberrant SRP19-RNA conformation.
12244299 crystal structure of a human SRP ternary complex consisting of SRP19, the M domain of SRP54 and the S domain of 7SL RNA
12050674 Structure of the SRP19 RNA complex
11641499 1.8 angstrom resolution crystal structure of human SRP19 in complex with its primary binding site on helix 6 of SRP RNA was determined

AA Sequence

KKKK                                                                      141 - 144

Text Mined References (25)

PMID Year Title
25944712 2015 N-terminome analysis of the human mitochondrial proteome.
22658674 2012 Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
21269460 2011 Initial characterization of the human central proteome.
20179341 2010 Structural insights into the assembly of the human and archaeal signal recognition particles.
18089836 2008 A new mechanism of 6-((2-(dimethylamino)ethyl)amino)-3-hydroxy-7H-indeno(2,1-c)quinolin-7-one dihydrochloride (TAS-103) action discovered by target screening with drug-immobilized affinity beads.
18029348 2008 Toward a confocal subcellular atlas of the human proteome.
17434535 2007 A threefold RNA-protein interface in the signal recognition particle gates native complex assembly.
16461635 2006 Decoding the fine-scale structure of a breast cancer genome and transcriptome.
16368877 2006 Genomic annotation of 15,809 ESTs identified from pooled early gestation human eyes.
16344560 2006 Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.