Property Summary

NCBI Gene PubMed Count 29
PubMed Score 110.78
PubTator Score 139.68

Knowledge Summary


No data available


  Disease Sources (2)

Disease Target Count P-value
posterior fossa group A ependymoma 1511 1.00961059424472E-11
malignant mesothelioma 3163 5.98767312717455E-6
pilocytic astrocytoma 3086 8.9967272612075E-6
adrenocortical carcinoma 1427 2.33523630064015E-5
Breast cancer 3099 0.00131225533467425
ductal carcinoma in situ 1745 0.00135903787357436
glioblastoma 5572 0.0020337382460892
adult high grade glioma 2148 0.00253562051261499
astrocytic glioma 2241 0.00313545214941422
atypical teratoid/rhabdoid tumor 1095 0.00348780223213868
oligodendroglioma 2849 0.00474612781993525
breast carcinoma 1614 0.00546349705205739
invasive ductal carcinoma 2950 0.00653743106882548
fibroadenoma 557 0.0127979648888401
Disease Target Count Z-score Confidence
lung cancer 4473 3.247 1.6


  Differential Expression (14)

Disease log2 FC p
malignant mesothelioma -1.500 0.000
astrocytic glioma 2.800 0.003
posterior fossa group A ependymoma 2.100 0.000
oligodendroglioma 2.200 0.005
glioblastoma 2.000 0.002
atypical teratoid/rhabdoid tumor 1.700 0.003
adrenocortical carcinoma -1.179 0.000
breast carcinoma -1.700 0.005
fibroadenoma -2.500 0.013
adult high grade glioma 1.700 0.003
pilocytic astrocytoma 1.600 0.000
ductal carcinoma in situ -2.000 0.001
invasive ductal carcinoma -2.100 0.007
Breast cancer 1.200 0.001


Accession P08949 Q96A06 Q96HH5




1C98   1C9A  

  Ortholog (6)

Gene RIF (12)

23879873 Rs2292462 was associated with left ventricular hypertrophy in type 2 diabetic patients.
21527296 There was no association between eating behaviour traits, or anthropometric variables, and NMB p.P73T polymorphism.
20010906 TT genotype of the NMB rs3809508 polymorphism was associated with a higher risk of obesity and moreover, the effects of this polymorphism on anthropometric values were influenced by the maternal educational level.
20010906 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18271693 No significant differences in the genotype distribution were demonstrated between normal weight and overweight/obese subjects
18271693 Observational study of gene-disease association. (HuGE Navigator)
17766645 REsults describe the expression of neuromedin B in adipose tissue and its regulation by changes in energy balance.
17299381 Observational study of gene-disease association. (HuGE Navigator)
15585758 Associated with eating behaviors
15528253 NMB and its receptor are coexpressed by proliferating cells in which they act in an autocrine fashion with similar and modest potency in both normal and malignant colonic epithelial cells.

AA Sequence


Text Mined References (30)

PMID Year Title
25416956 2014 A proteome-scale map of the human interactome network.
25123163 2014 Itch-associated peptides: RNA-Seq and bioinformatic analysis of natriuretic precursor peptide B and gastrin releasing peptide in dorsal root and trigeminal ganglia, and the spinal cord.
24092425 2013 Anti-EGFR therapy combined with neuromedin B receptor blockade induces the death of DAOY medulloblastoma cells.
24054546 2013 Functional bombesin receptors in urinary tract of rats and human but not of pigs and mice, an in vitro study.
23879873 2013 Genetic variants predicting left ventricular hypertrophy in a diabetic population: a Go-DARTS study including meta-analysis.
23317790 2013 The role of bombesin and bombesin-related peptides in the short-term control of food intake.
21712056 2011 Bombesin receptor subtype-3 agonists stimulate the growth of lung cancer cells and increase EGF receptor tyrosine phosphorylation.
21527296 2011 Effects of neuromedin-? on caloric compensation, eating behaviours and habitual food intake.
21140465 Biochemical specificity of von Economo neurons in hominoids.
21140464 The von Economo neurons in apes and humans.