Property Summary

NCBI Gene PubMed Count 10
PubMed Score 90.79
PubTator Score 28.79

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Sources (2)

Disease Target Count P-value
ovarian cancer 8492 1.92077758876193E-5
osteosarcoma 7933 6.11136975536919E-5
pancreatic ductal adenocarcinoma liver metastasis 1795 5.54588282518327E-4
pancreatic cancer 2300 8.08433506346564E-4
intraductal papillary-mucinous neoplasm (IPMN) 3289 0.00216825908801726
astrocytoma 1493 0.00406937824187984
Gaucher disease type 1 171 0.0119842418222559
Disease Target Count Z-score Confidence
Orotic aciduria 16 3.582 1.8

Expression

  Differential Expression (7)

Disease log2 FC p
osteosarcoma 1.803 0.000
astrocytoma 1.600 0.004
pancreatic ductal adenocarcinoma liver m... -1.413 0.001
intraductal papillary-mucinous neoplasm ... -1.600 0.002
ovarian cancer 2.300 0.000
Gaucher disease type 1 -1.500 0.012
pancreatic cancer -1.100 0.001

Synonym

Accession P08240 A6NIB3 B2R5Z8 B4E0H3 E9PJS4 Q9BVJ4 SR-alpha
Symbols DP
SRPR
Sralpha

Gene

PANTHER Protein Class (2)

PDB

5L3Q   2FH5   2GO5  

  Ortholog (14)

Species Source
Chimp OMA EggNOG
Macaque OMA EggNOG
Mouse OMA EggNOG Inparanoid
Rat OMA EggNOG
Dog OMA EggNOG
Horse OMA EggNOG
Cow OMA EggNOG
Pig OMA EggNOG
Opossum OMA EggNOG
Anole lizard OMA EggNOG
Xenopus OMA EggNOG
C. elegans OMA EggNOG
Fruitfly EggNOG Inparanoid
S.cerevisiae EggNOG Inparanoid

AA Sequence

MLDFFTIFSKGGLVLWCFQGVSDSCTGPVNALIRSVLLQERGGNNSFTHEALTLKYKLDNQFELVFVVGF      1 - 70
QKILTLTYVDKLIDDVHRLFRDKYRTEIQQQSALSLLNGTFDFQNDFLRLLREAEESSKIRAPTTMKKFE     71 - 140
DSEKAKKPVRSMIETRGEKPKEKAKNSKKKGAKKEGSDGPLATSKPVPAEKSGLPVGPENGVELSKEELI    141 - 210
RRKREEFIQKHGRGMEKSNKSTKSDAPKEKGKKAPRVWELGGCANKEVLDYSTPTTNGTPEAALSEDINL    211 - 280
IRGTGSGGQLQDLDCSSSDDEGAAQNSTKPSATKGTLGGMFGMLKGLVGSKSLSREDMESVLDKMRDHLI    281 - 350
AKNVAADIAVQLCESVANKLEGKVMGTFSTVTSTVKQALQESLVQILQPQRRVDMLRDIMDAQRRQRPYV    351 - 420
VTFCGVNGVGKSTNLAKISFWLLENGFSVLIAACDTFRAGAVEQLRTHTRRLSALHPPEKHGGRTMVQLF    421 - 490
EKGYGKDAAGIAMEAIAFARNQGFDVVLVDTAGRMQDNAPLMTALAKLITVNTPDLVLFVGEALVGNEAV    491 - 560
DQLVKFNRALADHSMAQTPRLIDGIVLTKFDTIDDKVGAAISMTYITSKPIVFVGTGQTYCDLRSLNAKA    561 - 630
VVAALMKA                                                                  631 - 638
//

Text Mined References (22)

PMID Year Title
25944712 2015 N-terminome analysis of the human mitochondrial proteome.
24275569 2014 An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
23186163 2013 Toward a comprehensive characterization of a human cancer cell phosphoproteome.
22658674 2012 Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.
22375059 2012 Different effects of Sec61?, Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells.
22223895 2012 Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-?-acetylation features.
21269460 2011 Initial characterization of the human central proteome.
20068231 2010 Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
19199708 2009 Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
18669648 2008 A quantitative atlas of mitotic phosphorylation.
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