| Tbio | Acylphosphatase-1 |
Its physiological role is not yet clear.
This gene is a member of the acylphosphatase family. The encoded protein is a small cytosolic enzyme that catalyzes the hydrolysis of the carboxyl-phosphate bond of acylphosphates. Two isoenzymes have been isolated and described based on their tissue localization: erythrocyte (common) type acylphosphatase encoded by this gene, and muscle type acylphosphatase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
This gene is a member of the acylphosphatase family. The encoded protein is a small cytosolic enzyme that catalyzes the hydrolysis of the carboxyl-phosphate bond of acylphosphates. Two isoenzymes have been isolated and described based on their tissue localization: erythrocyte (common) type acylphosphatase encoded by this gene, and muscle type acylphosphatase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Comments
| Disease | Target Count | P-value |
|---|---|---|
| Astrocytoma, Pilocytic | 3081 | 1.1e-04 |
| Pick disease | 1894 | 1.2e-04 |
| adult high grade glioma | 3801 | 3.3e-04 |
| osteosarcoma | 7950 | 6.5e-04 |
| intraductal papillary-mucinous carcinoma (IPMC) | 2989 | 1.3e-03 |
| glioblastoma | 5792 | 3.8e-03 |
| intraductal papillary-mucinous adenoma (IPMA) | 2955 | 4.1e-03 |
| intraductal papillary-mucinous neoplasm (IPMN) | 3291 | 5.5e-03 |
| lung cancer | 4740 | 7.6e-03 |
| astrocytic glioma | 2597 | 1.6e-02 |
| ovarian cancer | 8520 | 2.0e-02 |
| aldosterone-producing adenoma | 665 | 2.6e-02 |
| Disease | log2 FC | p |
|---|---|---|
| adult high grade glioma | -1.300 | 3.3e-04 |
| aldosterone-producing adenoma | -1.068 | 2.6e-02 |
| astrocytic glioma | -1.300 | 1.6e-02 |
| Astrocytoma, Pilocytic | -1.300 | 1.1e-04 |
| glioblastoma | -1.300 | 3.8e-03 |
| intraductal papillary-mucinous adenoma (... | 1.200 | 4.1e-03 |
| intraductal papillary-mucinous carcinoma... | 1.700 | 1.3e-03 |
| intraductal papillary-mucinous neoplasm ... | 2.000 | 5.5e-03 |
| lung cancer | 1.300 | 7.6e-03 |
| osteosarcoma | -1.758 | 6.5e-04 |
| ovarian cancer | 1.300 | 2.0e-02 |
| Pick disease | -1.300 | 1.2e-04 |
