Property Summary

NCBI Gene PubMed Count 178
Grant Count 2,029
R01 Count 1,025
Funding $290,247,362.72
PubMed Score 5615.43
PubTator Score 4955.22

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Relevance (73)

Disease Z-score Confidence
Cushing's syndrome 47 7.038 3.5
chronic kidney disease 90 6.253 3.1
post-traumatic stress disorder 45 5.324 2.7
Irritable bowel syndrome 59 5.233 2.6
Major Depressive Disorder 106 5.115 2.6
Pituitary-dependent Cushing's disease 8 5.034 2.5
Pituitary adenoma 35 4.858 2.4
Alcohol dependence 107 4.846 2.4
Adenoma 165 4.701 2.4
Hypoglycemia 81 4.701 2.4
Nelson syndrome 6 4.636 2.3
Anorexia nervosa 59 4.496 2.2
Addison's disease 29 4.376 2.2
Panic disorder 55 4.331 2.2
Hypopituitarism 36 4.277 2.1
Obesity 616 4.147 2.1
Hypertension 287 3.97 2.0
Adrenal adenoma 5 3.967 2.0
Substance abuse 55 3.952 2.0
Atypical depressive disorder 6 3.923 2.0
Pain agnosia 99 3.748 1.9
Amenorrhea 60 3.635 1.8
Melancholia 12 3.594 1.8
Withdrawal disorder 19 3.582 1.8
Drug dependence 2 3.541 1.8
Chronic fatigue syndrome 29 3.408 1.7
Fibromyalgia 22 3.384 1.7
Hypothyroidism 89 3.309 1.7
Generalized anxiety disorder 29 3.193 1.6
Alzheimer's disease 644 3.172 1.6
Bipolar Disorder 266 3.167 1.6
Cancer 2,346 3.108 1.6
Diabetes insipidus 14 3.088 1.5
Epilepsy 346 3.047 1.5
Neurohypophyseal diabetes insipidus 13 3.027 1.5
Acromegaly 40 3.008 1.5
ACTH Deficiency, Isolated 2
Alopecia 55
Anorexia 15
Anxiety Disorders 37
Bradycardia 24
Chest Pain 1
Cocaine-Related Disorders 88
Cognition Disorders 23
Cushing Syndrome 3
Delayed Puberty 10
Depressive disorder 48
Down syndrome 548
Fever 34
Hypotension 53
Movement Disorders 21
Pain 70
Pick disease 1,893
Pituitary apoplexy 3
Psychomotor Disorders 7
Retinitis 9
Seizures 95
Status Epilepticus 85
Stereotypic movement disorder 6
Substance Withdrawal Syndrome 52
Weight decreased 18
West Syndrome 23
astrocytic glioma 2,241
atypical teratoid/rhabdoid tumor 1,095
ependymoma 2,514
glioblastoma 5,572
medulloblastoma, large-cell 6,234
oligodendroglioma 2,849
osteosarcoma 7,933
pediatric high grade glioma 2,712
pilocytic astrocytoma 3,086
primitive neuroectodermal tumor 3,031
sonic hedgehog group medulloblastoma 1,482

Expression

  Differential Expression (13)

Disease log2 FC p
astrocytic glioma -3.000 0.005
ependymoma -3.500 0.004
oligodendroglioma -3.200 0.003
glioblastoma -3.000 0.000
osteosarcoma -2.545 0.002
sonic hedgehog group medulloblastoma -3.500 0.001
medulloblastoma, large-cell -1.300 0.033
primitive neuroectodermal tumor -2.400 0.011
pediatric high grade glioma -2.900 0.001
atypical teratoid/rhabdoid tumor -1.100 0.032
pilocytic astrocytoma -3.500 0.000
Pick disease -1.300 0.003
Down syndrome -2.000 0.002

Synonym

Accession P06850 B3KQS4
Symbols CRF
CRH1

Gene

CRH