Property Summary

NCBI Gene PubMed Count 821
Grant Count 2,395
R01 Count 1,589
Funding $196,401,867.25
PubMed Score 5981.79
PubTator Score 3644.48

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Relevance (63)

Disease Z-score Confidence
Cancer 2,346 6.411 3.2
Vascular disease 281 5.191 2.6
Toxic encephalopathy 131 4.027 2.0
diabetes mellitus 1,663 3.953 2.0
Arthritis 248 3.94 2.0
Alzheimer's disease 644 3.781 1.9
Obesity 616 3.674 1.8
Parkinson's disease 364 3.56 1.8
Lung disease 132 3.43 1.7
Eye disease 55 3.295 1.6
Kidney disease 396 3.246 1.6
Heart disease 279 3.201 1.6
Brain disease 83 3.069 1.5
Hyperglycemia 120 3.03 1.5
Liver disease 219 3.015 1.5
Amyotrophic Lateral Sclerosis 431
Brain Ischemia 87
Colonic Neoplasms 126
Heat Stroke 12
Hemangiosarcoma 18
Intestinal Polyps 5
Juvenile arthritis 124
Liver carcinoma 217
Liver neoplasms 109
Lung Neoplasms 171
Mammary Neoplasms 410
Mercury Poisoning, Nervous System 1
Neoplastic Cell Transformation 81
Peripheral Neuropathy 303
Reperfusion Injury 84
Rheumatoid Arthritis 1,160
Status Epilepticus 85
Stomach Neoplasms 282
Waldenstrons macroglobulinemia 765
acute myeloid leukemia 780
acute quadriplegic myopathy 1,157
aldosterone-producing adenoma 664
astrocytoma 1,493
atypical teratoid / rhabdoid tumor 4,369
breast carcinoma 1,614
chronic lymphosyte leukemia 232
colon cancer 1,475
fibroadenoma 557
gastric cancer 430
glioblastoma 5,572
group 4 medulloblastoma 1,875
hepatocellular carcinoma 532
inflammatory breast cancer 404
intraductal papillary-mucinous adenoma (... 2,956 
lung cancer 4,466
lung carcinoma 2,844
malignant mesothelioma 3,162
medulloblastoma, large-cell 6,234
nephrosclerosis 329
non-small cell lung cancer 2,798
osteosarcoma 7,933
ovarian cancer 8,484
pancreatic cancer 2,300
pancreatic carcinoma 567
pituitary cancer 1,972
psoriasis 6,685
pterygium 74
tuberculosis and treatment for 3 months 327

Expression

  Differential Expression (31)

Disease log2 FC p
Rheumatoid Arthritis 3.000 0.000
nephrosclerosis -1.157 0.000
gastric cancer -3.300 0.000
hepatocellular carcinoma -3.100 0.000
pancreatic cancer -2.600 0.000
Waldenstrons macroglobulinemia 1.058 0.002
malignant mesothelioma -2.200 0.000
chronic lymphosyte leukemia -1.100 0.002
astrocytoma 2.100 0.003
glioblastoma 2.000 0.005
atypical teratoid / rhabdoid tumor -1.100 0.008
medulloblastoma, large-cell -1.800 0.001
Amyotrophic Lateral Sclerosis 1.116 0.000
acute quadriplegic myopathy 1.343 0.000
tuberculosis and treatment for 3 months -1.900 0.000
non-small cell lung cancer -1.257 0.000
intraductal papillary-mucinous adenoma (... -1.300 0.012
lung cancer -2.700 0.000
colon cancer -1.600 0.003
breast carcinoma -1.800 0.000
fibroadenoma -1.800 0.024
group 4 medulloblastoma -1.800 0.000
pancreatic carcinoma -2.600 0.000
aldosterone-producing adenoma -1.841 0.013
psoriasis -2.700 0.000
inflammatory breast cancer -2.600 0.000
lung carcinoma -1.200 0.000
pterygium -1.300 0.046
acute myeloid leukemia 2.100 0.048
ovarian cancer 2.500 0.001
pituitary cancer -1.500 0.012

Synonym

Accession P05412 Q6FHM7 Q96G93
Symbols AP1
AP-1
c-Jun

Gene

JUN

PANTHER Protein Class (1)