Property Summary

NCBI Gene PubMed Count 1,481
Grant Count 5,175
R01 Count 3,005
Funding $593,199,653.34
PubMed Score 21900.25
PubTator Score 13414.46

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Relevance (128)

Disease Z-score Confidence
Acromegaly 40 7.986 4.0
Cancer 2,346 6.377 3.2
diabetes mellitus 1,663 6.173 3.1
Laron syndrome 9 6.112 3.1
Hypopituitarism 36 6.102 3.1
Obesity 616 5.681 2.8
Osteoporosis 257 5.615 2.8
Pituitary adenoma 35 5.61 2.8
Hypogonadism 70 5.509 2.8
Hyperinsulinism 63 5.303 2.7
Adenoma 165 5.296 2.6
Anorexia nervosa 59 5.217 2.6
Hypoglycemia 81 5.169 2.6
Hyperglycemia 120 5.034 2.5
Kidney disease 396 4.985 2.5
Polycystic Ovary Syndrome 332 4.822 2.4
Hypothyroidism 89 4.74 2.4
Myopathy 128 4.714 2.4
Retinopathy of prematurity 21 4.64 2.3
Hypertension 287 4.552 2.3
Hyperprolactinemia 22 4.515 2.3
Neurodegenerative disease 383 4.515 2.3
Metabolic syndrome X 155 4.397 2.2
Osteoarthritis 96 4.325 2.2
Donohue Syndrome 6 4.294 2.1
Heart disease 279 4.266 2.1
Prader-Willi syndrome 45 4.244 2.1
Diabetic Retinopathy 53 4.182 2.1
Liver disease 219 4.112 2.1
Amenorrhea 60 4.04 2.0
Hyperandrogenism 32 4.009 2.0
Coronary artery disease 240 3.919 2.0
Atherosclerosis 275 3.914 2.0
Craniopharyngioma 13 3.879 1.9
Hyperthyroidism 50 3.797 1.9
Goiter 27 3.738 1.9
Cerebrovascular disease 231 3.682 1.8
Short bowel syndrome 16 3.591 1.8
Cushing's syndrome 47 3.585 1.8
Metabolic acidosis 49 3.577 1.8
McCune Albright syndrome 19 3.572 1.8
Infertility 163 3.558 1.8
protein-energy malnutrition 8 3.476 1.7
Klinefelter's syndrome 59 3.474 1.7
Sleep apnea 7 3.449 1.7
Anovulation 20 3.261 1.6
Brain disease 83 3.243 1.6
Neuropathy 210 3.236 1.6
Lung disease 132 3.233 1.6
Hyperparathyroidism 43 3.219 1.6
Inflammatory bowel disease 142 3.219 1.6
Lipid metabolism disorder 102 3.209 1.6
Skin disease 65 3.195 1.6
Keratopathy 12 3.186 1.6
Silver-Russell syndrome 37 3.163 1.6
Graves' disease 25 3.127 1.6
Diffuse idiopathic skeletal hyperostosis 6 3.108 1.6
Dementia 129 3.007 1.5
Acquired metabolic disease 267 2.0
Acute kidney injury 65
Adverse reaction to drug 54
Alzheimer's disease 644
Amyotrophic Lateral Sclerosis 431
Atopic dermatitis 944
Autistic Disorder 320
Bladder Neoplasm 109
Breast cancer 3,094
Cardiomegaly 66
Cholestasis 93
Colitis 46
Corneal Diseases 3
Crohn Disease 97
Demyelinating Diseases 7
Diabetes Mellitus, Experimental 106
Diabetes Mellitus, Insulin-Dependent 76
Diabetic Cardiomyopathies 10
Diaphragmatic Hernia 40
Drug-Induced Liver Injury 118
Duchenne muscular dystrophy 602
Endometriosis 535
Female Urogenital Diseases 18
Hyperalgesia 71
Hypertensive disease 193
Insulin-Like Growth Factor I Deficiency 1
Kidney Diseases 86
Kidney Failure, Chronic 45
Liver Cirrhosis, Experimental 108
Mammary Neoplasms 410
Mammary Neoplasms, Experimental 150
Metabolic Bone Disorder 11
Muscular atrophy 67
Myocardial Ischemia 169
Neoplasm Invasiveness 127
Neoplasm Metastasis 138
Nerve Degeneration 73
Peripheral Neuropathy 303
Pituitary Neoplasms 6
Precocious puberty 4
Prostatic Neoplasms 471
Pulmonary Fibrosis 66
Spontaneous abortion 108
Type 2 diabetes mellitus 189 2.0
Uterine fibroid 29 1.0
acute quadriplegic myopathy 1,157
adrenocortical carcinoma 1,427
astrocytic glioma 2,241
autosomal dominant Emery-Dreifuss muscul... 499 
breast carcinoma 1,614
ductal carcinoma in situ 1,745
ependymoma 2,514
glioblastoma 5,572
group 4 medulloblastoma 1,875
interstitial cystitis 2,299
intraductal papillary-mucinous adenoma (... 2,956 
intraductal papillary-mucinous carcinoma... 2,988 
intraductal papillary-mucinous neoplasm ... 3,289 
invasive ductal carcinoma 2,950
juvenile dermatomyositis 1,189
limb girdle muscular dystrophy 2A 156
lung cancer 4,466
lung carcinoma 2,844
malignant mesothelioma 3,162
oligodendroglioma 2,849
ovarian cancer 8,484
pancreatic ductal adenocarcinoma liver m... 1,795 
pediatric high grade glioma 2,712
primary Sjogren syndrome 789
psoriasis 6,685

Expression

See source...

Synonym

Accession P05019 B2RWM7 E9PD02 P01343 Q14620 IGF-I
Symbols MGF
IGFI
IGF-I

Gene

PANTHER Protein Class (2)