Tbio IFNA4 Interferon alpha-4

Protein Summary

Description

Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.

Uniprot Accession IDs

• P05014
• P13358
• Q14CS4
• Q5VV15
• IFN-alpha-4

Gene Name

• IFNA4

Ensembl ID

• ENST00000421715
• ENSP00000412897
• ENSG00000236637

Symbol

• INFA4
• IFN-alpha4a

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
biological process	0.82
disease perturbation	0.62
kinase perturbation	0.54
pathway	0.54
transcription factor	0.54

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.87   (req: < 5)

Gene RIFs: 6   (req: <= 3)

Antibodies: 162   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.87   (req: >= 5)

Gene RIFs: 6   (req: > 3)

Antibodies: 162   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 15

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0