Property Summary

NCBI Gene PubMed Count 167
PubMed Score 1666.50
PubTator Score 998.80

Knowledge Summary


No data available


  Disease Sources (3)

Disease Target Count
Reperfusion Injury 84
Retinal Diseases 21
Disease Target Count P-value
posterior fossa group B ependymoma 1530 1.30481466685313E-12
Duchenne muscular dystrophy 602 1.06902828536506E-10
non-small cell lung cancer 2798 3.17809206292207E-10
malignant mesothelioma 3163 1.75085761402098E-9
oligodendroglioma 2849 2.27167927589673E-9
medulloblastoma 1524 3.08937121552069E-9
lung adenocarcinoma 2714 7.9707694264155E-9
atypical teratoid / rhabdoid tumor 4369 3.38154183813447E-7
ovarian cancer 8492 4.82529636479911E-6
adult high grade glioma 2148 3.34489081972426E-5
medulloblastoma, large-cell 6234 4.1496633766075E-5
pancreatic cancer 2300 8.21129010018405E-5
interstitial cystitis 2299 1.15304928246896E-4
primary pancreatic ductal adenocarcinoma 1271 1.36109762694453E-4
Becker muscular dystrophy 187 1.82868041552029E-4
ulcerative colitis 2087 3.30813249189672E-4
urothelial carcinoma 318 4.99137873813144E-4
intraductal papillary-mucinous adenoma (IPMA) 2956 6.6612305026007E-4
Down syndrome 548 7.03621907984079E-4
glioblastoma 5572 0.00144078456416508
cutaneous lupus erythematosus 1056 0.00157271967516854
intraductal papillary-mucinous carcinoma (IPMC) 2988 0.00235617231178879
primitive neuroectodermal tumor 3031 0.00261657388479413
astrocytic glioma 2241 0.00271507164625065
interstitial lung disease 292 0.00444570450122364
adrenocortical carcinoma 1427 0.00919494556176572
gastric carcinoma 832 0.00978306647034643
osteosarcoma 7933 0.0149245194261142
intraductal papillary-mucinous neoplasm (IPMN) 3289 0.0173136292285439
Pick disease 1893 0.0213661107069787
esophageal adenocarcinoma 737 0.0278894616611683
Breast cancer 3099 0.0298995673870555
Endometriosis 535 0.0455131185907221



Accession P04216 Q16008 Q9NSP1
Symbols CD90


  Ortholog (11)

Gene RIF (64)

26329007 CD90 is upregulated in gastric cancer and inhibits gastric cancer cell apoptosis by modulating the expression level of SPARC protein.
26272696 CD90+ liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA.
26191205 CD105+/CD90+ subpopulation from breast cancer MDA-MB-231 cells possesses "mesenchymal stem cell-like" characteristics, and its high migratory ability might be associated with epithelial-mesenchymal transformation.
26147640 we found that THY-1 mediates human cytomegalovirus infection at the entry step and is important for infection
25672610 these data suggest that CD90+CXCR4+ HCC cells may be CTSCs and selective elimination of these cells may substantially improve the current hepatocellular carcinoma therapy by reducing cancer metastasis.
25536077 CD90 could serve as a promising marker for pancreatic adenocarcinoma.
25216363 Dynamic catch of a Thy-1-integrin alpha5beta1+syndecan-4 trimolecular complex explains extraordinary cancer cell adhesion to the vascular endothelium.
25168019 CD133, CD44, and CD90 could be used as prognostic and predictive markers in hepatoblastoma.
25070848 TLR4 activation enhances the PD-L1-mediated tolerogenic capacity of colonic CD90+ stromal cells.
25061736 Wnt/beta-catenin aids in regulating the proliferation of hepG2 cells mediated by thy-1.

AA Sequence

SWLLLLLLSLSLLQATDFMSL                                                     141 - 161

Text Mined References (170)

PMID Year Title
26329007 2015 CD90 is upregulated in gastric cancer tissues and inhibits gastric cancer cell apoptosis by modulating the expression level of SPARC protein.
26272696 2015 CD90+ liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA.
26191205 2015 Isolation and characterization of CD105+/CD90+ subpopulation in breast cancer MDA-MB-231 cell line.
26147640 2015 THY-1 Cell Surface Antigen (CD90) Has an Important Role in the Initial Stage of Human Cytomegalovirus Infection.
25806121 2015 Glioblastoma specific antigens, GD2 and CD90, are not involved in cancer stemness.
25672610 2015 Evidence of CD90+CXCR4+ cells as circulating tumor stem cells in hepatocellular carcinoma.
25536077 2014 Overexpression of CD90 (Thy-1) in pancreatic adenocarcinoma present in the tumor microenvironment.
25416548 2015 Thy1 (CD90) controls adipogenesis by regulating activity of the Src family kinase, Fyn.
25300435 2014 Relative roles of CD90 and c-kit to the regenerative efficacy of cardiosphere-derived cells in humans and in a mouse model of myocardial infarction.
25300130 2014 Thy-1 modulates neurological cell-cell and cell-matrix interactions through multiple molecular interactions.