Property Summary

Ligand Count 9
NCBI Gene PubMed Count 463
PubMed Score 98804.88
PubTator Score 5011.65

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (6)

Disease Target Count Z-score Confidence
Hypertension 396 6.81 3.4
Pancreatitis 123 4.424 2.2
Thrombocytopenia 197 4.423 2.2
Uveitis 103 3.241 1.6
Urticaria 67 3.196 1.6
Acute kidney injury 70 0.0 0.0
Adenocarcinoma of lung 142 0.0 0.0
Angioedema 38 0.0 0.0
Anuria 9 0.0 0.0
Arthritis, Experimental 39 0.0 0.0
Azoospermia 110 0.0 0.0
Brain Diseases 24 0.0 0.0
Brain Injuries 65 0.0 0.0
Brain Ischemia 110 0.0 0.0
Cardiovascular Diseases 59 0.0 0.0
Chemical and Drug Induced Liver Injury 195 0.0 0.0
Depressive disorder 409 0.0 0.0
Diabetic Angiopathies 16 0.0 0.0
Diabetic Nephropathies 37 0.0 0.0
Disease Models, Animal 155 0.0 0.0
Drug-Related Side Effects and Adverse Reactions 62 0.0 0.0
Echinococcosis 26 0.0 0.0
Epilepsy 792 0.0 0.0
Fibrosis 44 0.0 0.0
Glomerulonephritis 46 0.0 0.0
Glomerulonephritis, Membranoproliferative 6 0.0 0.0
Glomerulonephritis, Membranous 7 0.0 0.0
HIV Infections 102 0.0 0.0
HIV Seropositivity 1 0.0 0.0
Heart Diseases 43 0.0 0.0
Heart failure 162 0.0 0.0
Hemolytic-Uremic Syndrome 30 0.0 0.0
Hepatitis 67 0.0 0.0
Hypersensitivity 63 0.0 0.0
Hypersensitivity, Delayed 1 0.0 0.0
Hyperthyroxinemia, Familial Dysalbuminemic 1 0.0 0.0
Hypoalbuminemia 24 0.0 0.0
Hypotension 82 0.0 0.0
Keloid 37 0.0 0.0
Kidney Diseases 114 0.0 0.0
Kidney Failure, Chronic 46 0.0 0.0
Liver Cirrhosis 181 0.0 0.0
Liver Cirrhosis, Experimental 769 0.0 0.0
Liver Failure, Acute 29 0.0 0.0
Meningitis, Aseptic 2 0.0 0.0
Muscular Diseases 27 0.0 0.0
Myocardial Reperfusion Injury 37 0.0 0.0
Nephritis 51 0.0 0.0
Nephritis, Interstitial 10 0.0 0.0
Nephrosis 21 0.0 0.0
Nephrotic Syndrome 78 0.0 0.0
Occupational Diseases 12 0.0 0.0
Pain 103 0.0 0.0
Pancreatic Diseases 8 0.0 0.0
Poisoning 16 0.0 0.0
Proteinuria 144 0.0 0.0
Respiratory Distress Syndrome, Adult 40 0.0 0.0
Respiratory Tract Diseases 6 0.0 0.0
Rhinitis, Allergic, Perennial 1 0.0 0.0
Serum Sickness 1 0.0 0.0
Stevens-Johnson syndrome 92 0.0 0.0
Stomach Neoplasms 300 0.0 0.0
Stroke 33 0.0 0.0
Disease Target Count Z-score Confidence
Carcinoma 11493 0.0 1.0
Liver cancer 604 0.0 0.5
Melanoma 711 0.0 0.6
Skin cancer 469 0.0 0.5
Disease Target Count Z-score Confidence
Kidney disease 430 8.26 4.0
diabetes mellitus 1728 7.512 3.8
Liver disease 237 7.317 3.7
Cancer 2499 6.574 3.3
Anemia 365 6.007 3.0
protein-energy malnutrition 8 6.004 3.0
Peritonitis 43 5.976 3.0
protein-losing enteropathy 12 5.789 2.9
Respiratory Failure 104 5.667 2.8
Portal hypertension 20 5.594 2.8
Cerebrovascular disease 238 5.529 2.8
Brain disease 96 5.517 2.8
Hepatitis B 108 5.516 2.8
Coronary artery disease 268 5.485 2.7
Heart disease 306 5.321 2.7
Bilirubin metabolic disorder 41 5.292 2.6
Atherosclerosis 291 5.259 2.6
Pneumonia 174 5.251 2.6
Hypersensitivity reaction type II disease 253 5.242 2.6
Diarrhea 253 5.213 2.6
Cholestasis 155 5.13 2.6
Diabetic retinopathy 56 5.118 2.6
Inflammatory bowel disease 151 5.091 2.5
Hyperglycemia 137 5.019 2.5
Esophageal varix 12 5.007 2.5
Obesity 678 4.995 2.5
Allergic hypersensitivity disease 126 4.907 2.5
Decubitus ulcer 13 4.87 2.4
Metabolic acidosis 90 4.845 2.4
Arthritis 290 4.821 2.4
Neuropathy 261 4.767 2.4
tuberculosis 2010 4.744 2.4
Varicose veins 20 4.716 2.4
Hyperparathyroidism 48 4.711 2.4
Peripheral vascular disease 87 4.692 2.3
Leukopenia 72 4.67 2.3
Hyperthyroxinemia 9 4.627 2.3
Lipid metabolism disorder 114 4.57 2.3
Asthma 385 4.562 2.3
Hepatitis C 94 4.545 2.3
Ovarian hyperstimulation syndrome 19 4.487 2.2
Cholangitis 32 4.256 2.1
Meningitis 67 4.231 2.1
Acquired immunodeficiency syndrome 197 4.23 2.1
Chronic obstructive pulmonary disease 184 4.225 2.1
Autonomic neuropathy 22 4.173 2.1
Hypercalcemia 59 4.16 2.1
Amyloidosis 67 4.147 2.1
Rhinitis 55 4.096 2.0
Arthus reaction 7 4.092 2.0
Intestinal Obstruction 31 4.085 2.0
Pulmonary embolism 55 4.083 2.0
Multiple Sclerosis 540 4.073 2.0
Neonatal Jaundice 30 4.057 2.0
Dementia 175 4.032 2.0
Portal vein thrombosis 12 3.995 2.0
Bronchitis 43 3.935 2.0
Acute cystitis 35 3.934 2.0
interstitial lung disease 298 3.926 2.0
Hyperphosphatemia 32 3.882 1.9
Kawasaki disease 28 3.866 1.9
Malaria 160 3.861 1.9
Hypothyroidism 122 3.84 1.9
Hyperhomocysteinemia 37 3.815 1.9
Tetanus 68 3.812 1.9
cystic fibrosis 1696 3.807 1.9
Pneumocystosis 17 3.787 1.9
Hyperuricemia 47 3.757 1.9
Short bowel syndrome 16 3.701 1.9
Vasculitis 80 3.661 1.8
Hyperthyroidism 53 3.655 1.8
Hypoglycemia 152 3.642 1.8
Mastitis 48 3.623 1.8
Fatty liver disease 103 3.612 1.8
Stomach disease 8 3.581 1.8
Alzheimer's disease 658 3.577 1.8
sarcoidosis 370 3.465 1.7
Schistosomiasis 35 3.452 1.7
Periodontal disease 40 3.408 1.7
Lymphedema 42 3.374 1.7
Exanthem 37 3.31 1.7
Leprosy 73 3.307 1.7
Dermatitis 157 3.293 1.6
Substance abuse 59 3.251 1.6
Diphtheria 40 3.225 1.6
Hypereosinophilic syndrome 71 3.21 1.6
Meningoencephalitis 13 3.207 1.6
Hypersplenism 10 3.204 1.6
Polyneuropathy 64 3.162 1.6
Tropical sprue 5 3.156 1.6
Capillary leak syndrome 4 3.15 1.6
Peptic ulcer disease 11 3.141 1.6
Hypertensive Retinopathy 14 3.14 1.6
Alcohol dependence 107 3.133 1.6
Thyrotoxicosis 38 3.105 1.6
Visceral leishmaniasis 14 3.1 1.5
Thrombophilia 38 3.097 1.5
Bronchiectasis 64 3.077 1.5
Toxic encephalopathy 141 3.055 1.5
Otitis Media 52 3.053 1.5
Primary immunodeficiency disease 54 3.032 1.5
Influenza 142 3.031 1.5
Hepatitis A 11 3.024 1.5

Expression

  Differential Expression (9)

See source...

Synonym

Accession P02768 E7ESS9 O95574 P04277 Q13140 Q645G4 Q68DN5 Q6UXK4 Q86YG0 Q8IUK7 Q9P157 Q9P1I7 Q9UHS3 Q9UJZ0
Symbols HSA
PRO0883
PRO0903
PRO1341

Gene

ALB

PANTHER Protein Class (1)

PDB

4K71   4N0F   4N0U   1AO6   1BJ5   1BKE   1BM0   1E78   1E7A   1E7B   1E7C   1E7E   1E7F   1E7G   1E7H   1E7I   1GNI   1GNJ   1H9Z   1HA2   1HK1   1HK2   1HK3   1HK4   1HK5   1N5U   1O9X   1TF0   1UOR   1YSX   2BX8   2BXA   2BXB   2BXC   2BXD   2BXE   2BXF   2BXG   2BXH   2BXI   2BXK   2BXL   2BXM   2BXN   2BXO   2BXP   2BXQ   2ESG   2I2Z   2I30   2N0X   2VDB   2VUE   2VUF   2XSI   2XVQ   2XVU   2XVV   2XVW   2XW0   2XW1   2YDF   3A73   3B9L   3B9M   3CX9   3JQZ   3JRY   3LU6   3LU7   3LU8   3SQJ   3TDL   3UIV   4BKE   4E99   4EMX   4G03   4G04   4HGK   4HGM   4IW1   4IW2   4K2C   4L8U   4L9K   4L9Q   4LA0   4LB2   4LB9   4S1Y   4Z69   5FUO   5GIX   5GIY   5ID7   5IFO   5IJF   5UJB   5X52  

  Ortholog (1)

Species Source Disease
Chimp OMA EggNOG

Gene RIF (344)

AA Sequence

MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEV      1 - 70
TEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLQHKDDNPNLPRLV     71 - 140
RPEVDVMCTAFHDNEETFLKKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELR    141 - 210
DEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADD    211 - 280
RADLAKYICENQDSISSKLKECCEKPLLEKSHCIAEVENDEMPADLPSLAADFVESKDVCKNYAEAKDVF    281 - 350
LGMFLYEYARRHPDYSVVLLLRLAKTYETTLEKCCAAADPHECYAKVFDEFKPLVEEPQNLIKQNCELFE    351 - 420
QLGEYKFQNALLVRYTKKVPQVSTPTLVEVSRNLGKVGSKCCKHPEAKRMPCAEDYLSVVLNQLCVLHEK    421 - 490
TPVSDRVTKCCTESLVNRRPCFSALEVDETYVPKEFNAETFTFHADICTLSEKERQIKKQTALVELVKHK    491 - 560
PKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGL                         561 - 609
//

Text Mined References (477)

PMID Year Title