Property Summary

NCBI Gene PubMed Count 810
Grant Count 3,546
R01 Count 2,086
Funding $303,074,026.65
PubMed Score 3644.81
PubTator Score 6881.77

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Relevance (59)

Disease Z-score Confidence
Arthritis 248 5.331 2.7
periodontitis 269 5.214 2.6
Cancer 2,346 4.856 2.4
Dermatitis 107 4.14 2.1
Hypersensitivity reaction type II diseas... 235  4.094 2.0
Lung disease 132 3.948 2.0
Vascular disease 281 3.944 2.0
Cholesteatoma 13 3.873 1.9
psoriasis 6,685 3.829 1.9
Eye disease 55 3.798 1.9
Alzheimer's disease 644 3.574 1.8
Acne 20 3.412 1.7
Bacterial vaginosis 15 3.395 1.7
Kidney disease 396 3.28 1.6
Inflammatory bowel disease 142 3.258 1.6
Hypercalcemia 37 3.179 1.6
Gingivitis 19 3.151 1.6
Chorioamnionitis 15 3.044 1.5
Amnesia 17
Ankylosing spondylitis 138 5.0
Anthracosis 4
Arsenic Poisoning 59
Brain Ischemia 87
Cardiomyopathies 90
Chondrosarcoma, Mesenchymal 5
Chronic progressive external ophthalmopl... 18 
Cryopyrin associated periodic syndrome 5
Dermatitis, Allergic Contact 66
Dermatologic disorders 65
Diarrhea 155
Drug-Induced Liver Injury 118
Endometriosis 535 1.0
Fever 34
HIV Wasting Syndrome 4
Heat Stroke 12
Hyperalgesia 71
Hypotension 53
Inflammation 109
Kearns-Sayre syndrome 6
MELAS syndrome 17
MERRF syndrome 5
Mitochondrial Myopathies 6
Myocardial Ischemia 169
Non-alcoholic Fatty Liver Disease 40
Optic Atrophy, Hereditary, Leber 14
Polymyositis 5
Reperfusion Injury 84
Schizophrenia 501 1.0
Skin Neoplasms 49
cutaneous lupus erythematosus 1,056
cystic fibrosis 1,665
dermatomyositis 933
hemolytic-uremic syndrome 28
lung cancer 4,466
lung carcinoma 2,844
malignant mesothelioma 3,162
oligodendroglioma 2,849
tuberculosis 1,557
ulcerative colitis 2,087

Expression

  Differential Expression (8)

Disease log2 FC p
malignant mesothelioma -3.500 0.000
oligodendroglioma -1.100 0.027
cutaneous lupus erythematosus 1.800 0.011
cystic fibrosis 1.683 0.000
tuberculosis -7.300 0.000
lung cancer -1.500 0.000
lung carcinoma -1.900 0.000
ulcerative colitis 2.500 0.000

Synonym

Accession P01583 Q53QF9 Q7RU02 IL-1 alpha
Symbols IL1
IL-1A
IL1F1
IL1-ALPHA

Gene