Property Summary

NCBI Gene PubMed Count 759
Grant Count 28,925
R01 Count 14,292
Funding $5,935,305,339.5
PubMed Score 141255.37
PubTator Score 51392.55

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Relevance (128)

Disease Z-score Confidence
diabetes mellitus 1,663 9.701 4.0
Hypoglycemia 81 8.761 4.0
Hyperglycemia 120 8.487 4.0
Obesity 616 8.295 4.0
Hyperinsulinism 63 8.186 4.0
Metabolic syndrome X 155 7.559 3.8
Polycystic Ovary Syndrome 332 7.142 3.6
Hypertension 287 6.892 3.4
Lipid metabolism disorder 102 6.566 3.3
Coronary artery disease 240 6.243 3.1
Kidney disease 396 6.127 3.1
Hyperandrogenism 32 6.055 3.0
Atherosclerosis 275 5.923 3.0
Acanthosis nigricans 14 5.907 3.0
Fatty liver disease 84 5.877 2.9
Adenoma 165 5.704 2.9
Hyperinsulinemic hypoglycemia 17 5.578 2.8
Neuropathy 210 5.506 2.8
Diabetic Retinopathy 53 5.505 2.8
Cancer 2,346 5.476 2.7
Lipodystrophy 32 5.384 2.7
Heart disease 279 5.291 2.6
Pancreatitis 97 5.273 2.6
maturity-onset diabetes of the young 28 5.24 2.6
Anovulation 20 5.232 2.6
Autonomic neuropathy 21 5.176 2.6
Liver disease 219 5.114 2.6
Cerebrovascular disease 231 5.045 2.5
Acromegaly 40 4.948 2.5
Lactic acidosis 42 4.938 2.5
Hypersensitivity reaction type II diseas... 235  4.842 2.4
Donohue Syndrome 6 4.689 2.3
Hypothyroidism 89 4.688 2.3
Hypopituitarism 36 4.622 2.3
Eating disorder 24 4.428 2.2
Alzheimer's disease 644 4.425 2.2
Hyperthyroidism 50 4.333 2.2
Infertility 163 4.327 2.2
Brain disease 83 4.31 2.2
Allergic hypersensitivity disease 123 4.306 2.2
Peripheral vascular disease 90 4.184 2.1
Cushing's syndrome 47 4.177 2.1
Hypokalemia 40 4.163 2.1
Hypogonadism 70 4.154 2.1
Duodenal ulcer 20 4.148 2.1
Amenorrhea 60 4.094 2.0
Hyperuricemia 35 4.041 2.0
Obstructive sleep apnea 28 3.971 2.0
Schizophrenia 501 3.854 1.9
cystic fibrosis 1,665 3.836 1.9
Dementia 129 3.769 1.9
Diarrhea 155 3.76 1.9
Dumping syndrome 9 3.756 1.9
Myopathy 128 3.703 1.9
Osteoporosis 257 3.633 1.8
Blindness 84 3.585 1.8
Thyrotoxicosis 38 3.583 1.8
Hyperprolactinemia 22 3.557 1.8
Prader-Willi syndrome 45 3.544 1.8
Lung disease 132 3.517 1.8
Gastroparesis 20 3.494 1.7
Anemia 252 3.354 1.7
Impotence 45 3.315 1.7
Addison's disease 29 3.265 1.6
protein-energy malnutrition 8 3.22 1.6
Arthritis 248 3.216 1.6
Glycogen storage disease 37 3.214 1.6
Pituitary adenoma 35 3.212 1.6
Hepatitis C 90 3.206 1.6
Cataract 104 3.196 1.6
Wolfram syndrome 11 3.15 1.6
Steatorrhea 20 3.144 1.6
Macular retinal edema 11 3.129 1.6
Pancreatic agenesis 14 3.123 1.6
Exocrine pancreatic insufficiency 21 3.107 1.6
Hyperparathyroidism 43 3.107 1.6
ADULT syndrome 9 3.047 1.5
22q13.3 Deletion Syndrome 2
Acute kidney injury 65
Albuminuria 20
Bipolar Disorder 266
Cardiac arrest 26
Cystic Kidney Diseases 6
DIABETES MELLITUS, INSULIN-DEPENDENT, 2 1
DIABETES MELLITUS, PERMANENT NEONATAL 5
Diabetes Mellitus, Insulin-Dependent 76
Diabetes Mellitus, Non-Insulin-Dependent 157
Diabetic Cardiomyopathies 10
Diabetic Ketoacidosis 1
Diabetic Nephropathy 37
Edema 38
Fatty Liver 48
Heart failure 80
Hepatitis 61
Hyperkalemia 2
Hyperproinsulinemia 1
Hypertensive disease 193
Hypertriglyceridemia 18
Hypertrophic Cardiomyopathy 56
Hypotension 53
Impaired glucose tolerance 12
Insulin Resistance 48
Lewy Body Disease 19
Liver Failure, Acute 22
Maturity-Onset Diabetes of the Young, Ty... 2 
Maturity-onset diabetes of the young, ty... 1 
Memory Disorders 36
Metabolic Diseases 9
Neural Tube Defects 27
Neurocognitive Disorders 1
Panic disorder 55
Paralysed 9
Paresthesia 2
Parkinson Disease 102
Prostatic Neoplasms 471
Renal Insufficiency 10
Rhabdomyolysis 2
Seizures 95
Tachycardia 17
Type 1 diabetes mellitus 101 5.0
Urinary Bladder Diseases 5
Ventricular Dysfunction, Left 15
Ventricular Fibrillation 10
Ventricular Outflow Obstruction 1
Weight decreased 18
intraductal papillary-mucinous adenoma (... 2,956 
intraductal papillary-mucinous carcinoma... 2,988 
intraductal papillary-mucinous neoplasm ... 3,289 

Expression

See source...

Synonym

Accession P01308 Q5EEX2
Symbols IDDM
ILPR
IRDN
IDDM1
IDDM2
MODY10

Gene

INS

PANTHER Protein Class (2)