Property Summary

NCBI Gene PubMed Count 259
PubMed Score 20357.69
PubTator Score 13052.68

Knowledge Summary


No data available


  Disease Sources (3)


Accession P01270 Q4VB48 Q9UD38 PTH
Symbols PTH1



PANTHER Protein Class (2)


1BWX   1ET1   1ET2   1FVY   1HPH   1HPY   1HTH   1ZWA   1ZWB   1ZWD   1ZWE   1ZWF   1ZWG   2L1X   3C4M  

  Ortholog (8)

Gene RIF (221)

27012036 Abnormal diurnal patterns of PTH are associated with sustained mild hypercalcemia in nondialyzed chronic kidney disease patients.
26997379 Serum secreted i-PTH level might not be predictable by a total mass of parathyroid glands or by their blood supply.
26867053 In this large community-based cohort, PTH levels, overall, were not independently associated with the risk of hypertension. However, we found some evidence that PTH may be associated with hypertension in blacks.
26834008 results suggest that NO-mediated vasorelaxation plays partly a role in the anabolic action of PTH on cortical bone
26662934 Data suggest that effects of PTH on bone remodeling are mediated not only by osteoblasts/osteocytes but also by T-lymphocytes in bone marrow; T-lymphocytes regulate differentiation/life span of stromal cells and their responsiveness to PTH. [REVIEW]
26451492 PTH does not contribute to the occurrence of metabolic components of obesity, but there is a positive correlation between 25(OH)D and HDL-C.
26398210 Elevation of PTH, unlike vitamin D, is independently associated with Chronic Obstructive Pulmonary Disease (COPD) severity, and may be a better biomarker for COPD.
26339419 Study indicates significant association between specific PTH gene promoter region variants and altered levels of 25(OH)D and vitamin D deficiency among specific nationals.
26299086 Suggest that measurement of iPTH may be useful for assessment of mineral bone disorder in patients with chronic kidney disease.
26287968 recombinant human klotho inhibits the expression of 1-OH by PTH both in vitro and in vivo.

AA Sequence


Text Mined References (261)

PMID Year Title
27012036 2016 Abnormal Diurnal Patterns of Parathyroid Hormone are Associated with Sustained Mild Hypercalcemia in Non-Dialyzed Chronic Kidney Disease.
26997379 2016 The relationship between total mass and blood supply of parathyroid glands and their secretion of parathyroid hormone in hemodialysis patients with secondary hyperparathyroidism.
26867053 2016 Parathyroid hormone and the risk of incident hypertension: the Atherosclerosis Risk in Communities study.
26834008 2016 The anabolic action of intermittent parathyroid hormone on cortical bone depends partly on its ability to induce nitric oxide-mediated vasorelaxation in BALB/c mice.
26662934 2016 T cells, osteoblasts, and osteocytes: interacting lineages key for the bone anabolic and catabolic activities of parathyroid hormone.
26451492 2015 Relationship Between Parathormone and Obesity-Linked Disorders.
26398210 2015 Parathyroid Hormone as a Novel Biomarker for Chronic Obstructive Pulmonary Disease: Korean National Health and Nutrition Examination Survey.
26339419 2015 Association between promoter region genetic variants of PTH SNPs and serum 25(OH)-vitamin D level.
26303600 2015 PTH receptor-1 signalling-mechanistic insights and therapeutic prospects.
26299086 2015 Alkaline Phosphatase, iPTH and Bone Turnover Markers in Chinese Advanced Chronic Kidney Disease Patients.