Property Summary

NCBI Gene PubMed Count 262
Grant Count 2,358
R01 Count 1,341
Funding $255,476,084.19
PubMed Score 36028.76
PubTator Score 11417.61

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Relevance (173)

Disease Z-score Confidence
Cushing's syndrome 47 8.602 4.0
Adenoma 165 6.976 3.5
Pituitary adenoma 35 6.864 3.4
Nelson syndrome 6 6.791 3.4
Hypopituitarism 36 6.583 3.3
Congenital adrenal hyperplasia 74 6.521 3.3
Addison's disease 29 6.293 3.1
Pituitary-dependent Cushing's disease 8 6.057 3.0
Hypoglycemia 81 6.05 3.0
Pain agnosia 99 6.003 3.0
Kidney disease 396 5.753 2.9
Obesity 616 5.706 2.9
Conn's syndrome 22 5.669 2.8
Hypertension 287 5.61 2.8
Adrenal cortical adenoma 10 5.558 2.8
Hypokalemia 40 5.407 2.7
Amenorrhea 60 5.329 2.7
Hyperaldosteronism 27 5.276 2.6
Hyperprolactinemia 22 5.22 2.6
Hyperandrogenism 32 5.114 2.6
Primary pigmented nodular adrenocortical... 12  5.101 2.6
Cancer 2,346 5.076 2.5
Epilepsy 346 5.06 2.5
triple-A syndrome 18 5.046 2.5
Hypothyroidism 89 5.02 2.5
Polycystic Ovary Syndrome 332 4.961 2.5
Pituitary apoplexy 3 4.872 2.4
Acromegaly 40 4.844 2.4
Anxiety disorder 22 4.719 2.4
diabetes mellitus 1,663 4.646 2.3
Rheumatic fever 16 4.629 2.3
Achalasia 11 4.495 2.2
Anorexia nervosa 59 4.443 2.2
Alcohol dependence 107 4.427 2.2
Hypogonadism 70 4.39 2.2
Asthma 349 4.388 2.2
Major Depressive Disorder 106 4.388 2.2
Arthritis 248 4.349 2.2
tuberculosis 1,557 4.319 2.2
Hypersensitivity reaction type II diseas... 235  4.266 2.1
Craniopharyngioma 13 4.21 2.1
Hyperglycemia 120 4.177 2.1
Neurohypophyseal diabetes insipidus 13 4.037 2.0
Hypothalamic disease 3 3.943 2.0
Empty sella syndrome 6 3.927 2.0
Skin disease 65 3.924 2.0
Carney complex 23 3.896 1.9
Adrenoleukodystrophy 31 3.887 1.9
Multiple Sclerosis 498 3.782 1.9
Myopathy 128 3.738 1.9
Pseudohermaphroditism 16 3.723 1.9
Hyperthyroidism 50 3.703 1.9
Substance abuse 55 3.684 1.8
Neuropathy 210 3.671 1.8
Inappropriate ADH syndrome 5 3.665 1.8
Withdrawal disorder 19 3.624 1.8
Melancholia 12 3.617 1.8
Klinefelter's syndrome 59 3.602 1.8
Infertility 163 3.591 1.8
Amnestic disorder 37 3.522 1.8
Hyperinsulinism 63 3.521 1.8
Schizophrenia 501 3.506 1.8
Osteoporosis 257 3.482 1.7
Chronic fatigue syndrome 29 3.478 1.7
Tuberous sclerosis 18 3.466 1.7
Lung disease 132 3.398 1.7
Leydig cell tumor 9 3.348 1.7
Trichinosis 7 3.342 1.7
Phaeochromocytoma 20 3.324 1.7
Heart disease 279 3.285 1.6
Metabolic syndrome X 155 3.278 1.6
Gynecomastia 13 3.218 1.6
Alopecia 55 3.194 1.6
McCune Albright syndrome 19 3.175 1.6
Congenital adrenal insufficiency 7 3.172 1.6
Cerebrovascular disease 231 3.131 1.6
Allergic hypersensitivity disease 123 3.129 1.6
Drug dependence 2 3.108 1.6
Bronchus adenoma 1 3.105 1.6
Inflammatory bowel disease 142 3.103 1.6
Thyroiditis 25 3.092 1.5
Meningitis 46 3.057 1.5
Migraine 79 3.039 1.5
Liver disease 219 3.032 1.5
Anovulation 20 3.018 1.5
Eye disease 55 3.011 1.5
ACTH Syndrome, Ectopic 1
Acute Kidney Tubular Necrosis 6
Adrenal Cortex Diseases 1
Amnesia 17
Anoxia 33
Arthritis, Gouty 1
Autistic Disorder 320
Bipolar Disorder 266
Body Weight 14
Bradycardia 24
Calcinosis 62
Calcium pyrophosphate deposition disease 1
Cardiomegaly 66
Cardiomyopathies 90
Catalepsy 15
Cerebral Hemorrhage 27
Cerebral palsy 28
Cholestasis 93
Cocaine-Related Disorders 88
Constipation 43
Cushing Syndrome 3
Cystitis 16
Depressive disorder 48
Diabetes insipidus 14
Disorder of eye 7
Edema 38
Epilepsies, Myoclonic 5
Eye pain 1
Facial paralysis 15
Fatty Liver 48
Femur Head Necrosis 2
Fever 34
Gastrointestinal Diseases 12
Glomerulonephritis 36
Heart failure 80
Hematuria 5
Hemorrhage 18
Heroin dependence 30
Hirsutism 2
Hypercalciuria 3
Hypernatremia 1
Hypertensive disease 193
Hypertrophic Cardiomyopathy 56
Hypocalcemia 5
Hypotension 53
Immune System Diseases 4
Infection 5
Kidney Calculi 7
Kidney Diseases 86
Liver Cirrhosis, Experimental 108
Liver Failure, Acute 22
Long QT syndrome 52
Melanoma 261
Mental disorders 11
Myasthenia Gravis 26
Myocardial Ischemia 169
Nausea 9
Necrosis 51
Nephrocalcinosis 18
Neurogenic Inflammation 12
Oliguria 3
Opsoclonus-Myoclonus Syndrome 1
Pain 70
Pancreatic Diseases 6
Penile Diseases 3
Pneumonia 133
Postoperative Complications 4
Proopiomelanocortin Deficiency 1
Proteinuria 63
Renal Cell Carcinoma 199
Restless legs syndrome 28
Rhabdomyoma 1
Sacroiliitis 1
Seizures 95
Sick sinus syndrome 14
Sleep Wake Disorders 5
Subaortic stenosis 1
Substance Withdrawal Syndrome 52
Synovitis 38
Tonic-clonic epilepsy 47
Urinary tract infection 2
Weight Gain 87
Weight decreased 18
West Syndrome 23
adult high grade glioma 2,148
breast carcinoma 1,614
pituitary cancer 1,972

Expression

  Differential Expression (3)

Disease log2 FC p
breast carcinoma -1.100 0.004
adult high grade glioma -1.100 0.002
pituitary cancer -8.000 0.000

Synonym

Accession P01189 P78442 Q53T23 Q9UD39 Q9UD40 POMC
Symbols LPH
MSH
NPP
POC
ACTH
CLIP

Gene