Property Summary

NCBI Gene PubMed Count 307
Grant Count 3,302
R01 Count 2,045
Funding $371,141,077.93
PubMed Score 13094.72
PubTator Score 3823.55

Knowledge Summary

Patent

No data available

TINX Plot

  Disease Relevance (86)

Disease Z-score Confidence
Cancer 2,346 5.833 2.9
Pain agnosia 99 4.818 2.4
Migraine 79 4.666 2.3
Epilepsy 346 4.645 2.3
Schizophrenia 501 4.645 2.3
Morphine dependence 19 4.35 2.2
Withdrawal disorder 19 4.308 2.2
Osteoporosis 257 4.302 2.2
Arthritis 248 4.121 2.1
Hypertension 287 4.1 2.1
post-traumatic stress disorder 45 4.025 2.0
Gastrointestinal system disease 50 3.992 2.0
Toxic encephalopathy 131 3.911 2.0
Parkinson's disease 364 3.855 1.9
Obesity 616 3.688 1.8
Alzheimer's disease 644 3.671 1.8
Amnestic disorder 37 3.562 1.8
Kidney disease 396 3.472 1.7
Cerebrovascular disease 231 3.408 1.7
Motion sickness 32 3.321 1.7
Atherosclerosis 275 3.254 1.6
Hypoglycemia 81 3.244 1.6
Cystitis 16 3.243 1.6
Eye disease 55 3.228 1.6
Irritable bowel syndrome 59 3.218 1.6
Fibrous dysplasia 15 3.173 1.6
Osteopetrosis 40 3.148 1.6
Sudden infant death syndrome 33 3.133 1.6
Attention deficit hyperactivity disorder 156 3.037 1.5
Narcolepsy 58 3.024 1.5
diabetes mellitus 1,663 3.003 1.5
AMYOTROPHIC LATERAL SCLEROSIS 1 49
Amphetamine-Related Disorders 74
Anxiety Disorders 37
Cocaine-Related Disorders 88
Down syndrome 548
Endometriosis 535
Heat Stroke 12
Hemorrhage 18
Hyperactive behavior 31
Hypertensive disease 193
Infarction, Middle Cerebral Artery 25
Juvenile arthritis 124
Lipoatrophic Diabetes Mellitus 5
Liver carcinoma 217
Lung Neoplasms 171
Mammary Neoplasms 410
Neurotoxicity Syndromes 26
Osteitis Fibrosa Disseminata 2
Reperfusion Injury 84
Rheumatoid Arthritis 1,160
Seizures 95
Status Epilepticus 85
Substance Withdrawal Syndrome 52
Waldenstrons macroglobulinemia 765
acute myeloid leukemia 780
adrenocortical carcinoma 1,427
aldosterone-producing adenoma 664
astrocytoma 1,493
breast carcinoma 1,614
chronic lymphosyte leukemia 232
colon cancer 1,475
fascioscapulohumeral muscular dystrophy 100
fibroadenoma 557
gastric cancer 430
glioblastoma 5,572
group 4 medulloblastoma 1,875
hepatocellular carcinoma 532
inflammatory breast cancer 404
limb girdle muscular dystrophy 2I 56
lung adenocarcinoma 2,713
lung cancer 4,466
lung carcinoma 2,844
malignant mesothelioma 3,162
nephrosclerosis 329
nervous system disorder 53
non primary Sjogren syndrome sicca 840
non-small cell lung cancer 2,798
ovarian cancer 8,484
periodontitis 269
pituitary cancer 1,972
posterior fossa group A ependymoma 1,511
psoriasis 6,685
pterygium 74
ulcerative colitis 2,087
urothelial carcinoma 318

Expression

  Differential Expression (33)

Disease log2 FC p
Rheumatoid Arthritis 1.800 0.001
nephrosclerosis -2.599 0.001
gastric cancer -1.700 0.000
hepatocellular carcinoma -1.200 0.006
Waldenstrons macroglobulinemia 1.126 0.049
urothelial carcinoma -2.900 0.002
malignant mesothelioma 1.200 0.000
chronic lymphosyte leukemia -3.300 0.000
group 4 medulloblastoma -2.400 0.006
astrocytoma 3.300 0.002
glioblastoma 3.300 0.001
periodontitis 1.200 0.000
limb girdle muscular dystrophy 2I 1.974 0.031
fascioscapulohumeral muscular dystrophy 1.962 0.005
adrenocortical carcinoma -2.000 0.006
non-small cell lung cancer -2.300 0.022
lung cancer -3.900 0.000
colon cancer -2.500 0.020
breast carcinoma -2.100 0.000
fibroadenoma -2.700 0.010
lung adenocarcinoma -1.300 0.000
posterior fossa group A ependymoma 1.300 0.010
non primary Sjogren syndrome sicca -1.400 0.029
aldosterone-producing adenoma -2.293 0.015
psoriasis -3.400 0.000
inflammatory breast cancer -5.700 0.000
lung carcinoma -2.400 0.000
pterygium -3.500 0.027
acute myeloid leukemia 1.400 0.031
ulcerative colitis 2.600 0.001
ovarian cancer 2.300 0.002
pituitary cancer -3.800 0.000
Down syndrome 1.300 0.034

Synonym

Accession P01100 A8K4E2 B4DQ65 P18849
Symbols p55
AP-1
C-FOS

Gene

FOS

PANTHER Protein Class (1)