Property Summary

NCBI Gene PubMed Count 4,127
Grant Count 6,664
R01 Count 3,613
Funding $850,681,930.79
PubMed Score 9318.14
PubTator Score 20799.95

Knowledge Summary

Patent (1,239,008)

TINX Plot

  Disease Relevance (95)

Disease Z-score Confidence
Cancer 2,346 8.112 4.0
Exanthem 39 5.713 2.9
Diarrhea 155 5.036 2.5
ductal carcinoma in situ 1,745 4.634 2.3
Neutropenia 78 4.328 2.2
Paronychia 7 4.106 2.1
Stomatitis 19 3.705 1.9
Adenoma 165 3.326 1.7
Adenocarcinoma in situ 15 3.325 1.7
Acute kidney injury 65
Adenocarcinoma 115
Adenocarcinoma of lung (disorder) 48
Adenocarcinoma of pancreas 12
Animal Mammary Neoplasms 136
Arthritis, Experimental 39
Autosomal Recessive Polycystic Kidney Di... 5 
Bile Duct Neoplasms 1
Bladder Neoplasm 109
Brain cancer 21 2.0
Breast cancer 3,094 1.0
Carcinoma 2,147 3.0
Carcinoma of thyroid 17
Cardiomyopathy, Dilated 47
Chloracne 32
Cholangiocarcinoma 32
Colonic Neoplasms 126
Colorectal Neoplasms 217
Craniofacial Abnormalities 147
DOID:2627 14 1.0
Diabetes Mellitus, Non-Insulin-Dependent 157
Disease Progression 125
Endometriosis 535
Esophageal Neoplasms 67
Giant Cell Glioblastoma 12
Glioma 65
HER2 Positive Carcinoma of Breast 2
Head and Neck Neoplasms 23
INFLAMMATORY SKIN AND BOWEL DISEASE, NEO... 1 
Insulin Resistance 48
Kidney cancer 118 1.0
Liver carcinoma 217
Lung Neoplasms 171
Malignant glioma 23 2.0
Malignant tumor of colon 3
Mammary Neoplasms 410
Mammary Neoplasms, Experimental 150
Mesothelioma 40
Nasopharyngeal Neoplasms 8
Neoplasm Invasiveness 127
Neoplasm Metastasis 138
Neoplasm Recurrence, Local 23
Non-small cell lung cancer, positive for... 4 
Papilloma 27
Pick disease 1,893
Prostatic Neoplasms 471
Rectal Neoplasms 7
Rheumatoid Arthritis 1,160
Secondary malignant neoplasm of colon 2
Small cell carcinoma of lung 45
Squamous cell carcinoma 94
Squamous cell carcinoma of esophagus 82
Squamous cell carcinoma of larynx 1
Squamous cell carcinoma of mouth 1
Squamous cell carcinoma of nose 1
Squamous cell carcinoma of pharynx 1
Squamous cell carcinoma of the head and ... 24 
Stomach Neoplasms 282
Uterine Cervical Neoplasm 21
acute quadriplegic myopathy 1,157
adrenocortical carcinoma 1,427
adult high grade glioma 2,148
astrocytic glioma 2,241
atypical teratoid / rhabdoid tumor 4,369
breast carcinoma 1,614
cutaneous lupus erythematosus 1,056
gallbladder neoplasm 9
glioblastoma 5,572
gliosarcoma 19
interstitial cystitis 2,299
invasive ductal carcinoma 2,950
lung cancer 4,466 3.0
medulloblastoma 1,524
medulloblastoma, large-cell 6,234
non-small cell lung cancer 2,798
non-small cell lung carcinoma 413
oligodendroglioma 2,849
osteosarcoma 7,933
ovarian cancer 8,484
ovarian neoplasm 97
pancreatic ductal adenocarcinoma liver m... 1,795 
pilocytic astrocytoma 3,086
pituitary cancer 1,972
sarcoidosis 358
spina bifida 1,064
subependymal giant cell astrocytoma 2,287

Expression

  Differential Expression (26)

Disease log2 FC p
glioblastoma 3.400 0.000
osteosarcoma 2.175 0.000
Rheumatoid Arthritis 1.700 0.001
astrocytic glioma 3.100 0.005
oligodendroglioma 3.100 0.002
cutaneous lupus erythematosus -1.800 0.005
medulloblastoma 2.400 0.010
atypical teratoid / rhabdoid tumor 3.600 0.000
medulloblastoma, large-cell 4.700 0.000
acute quadriplegic myopathy 1.302 0.003
breast carcinoma -2.300 0.000
pancreatic ductal adenocarcinoma liver m... -1.253 0.008
non-small cell lung cancer 1.387 0.000
lung cancer -5.000 0.000
interstitial cystitis -1.200 0.001
adult high grade glioma 3.300 0.001
pilocytic astrocytoma -1.700 0.000
subependymal giant cell astrocytoma 1.612 0.027
invasive ductal carcinoma -2.218 0.000
spina bifida -1.926 0.017
Pick disease 2.000 0.000
Breast cancer -3.100 0.000
ductal carcinoma in situ -1.600 0.042
ovarian cancer 2.700 0.000
pituitary cancer -2.000 0.000
sarcoidosis 1.300 0.014

Synonym

Accession P00533 O00688 O00732 P06268 Q14225 Q68GS5 Q92795 Q9BZS2 Q9GZX1 Q9H2C9 Q9H3C9 Q9UMD7 Q9UMD8 Q9UMG5
Symbols ERBB
HER1
mENA
ERBB1
PIG61
NISBD2

Gene