Tbio ODF4 Outer dense fiber protein 4

Protein Summary

Description

Component of the outer dense fibers (ODF) of spermatozoa which could be involved in sperm tail structure, sperm movement and general organization of cellular cytoskeleton. This gene encodes a protein that is localized in the outer dense fibers of the tails of mature sperm. This protein is thought to have some important role in the sperm tail. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

Uniprot Accession IDs

• Q2M2E3
• Q8J021

Gene Name

• ODF4

Ensembl ID

• ENST00000328248
• ENSP00000331086
• ENSG00000184650

Symbol

• OPPO1
• CT134
• CT136
• OPPO1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
gene perturbation	0.65
tissue	0.62
tissue sample	0.44
cell line	0.41
cellular component	0.36

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.18   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 53   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 11.18   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 53   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0