ASMTL
N-acetylserotonin O-methyltransferase-like protein
Protein Summary
Unknown. The presence of the putative catalytic domain of S-adenosyl-L-methionine binding argues for a methyltransferase activity. The protein encoded by this gene has an N-terminus that is similar to the multicopy associated filamentation (maf) protein of Bacillus subtilis and to orfE of Escherichia coli, while the C-terminus is similar to N-acetylserotonin O-methyltransferase. This gene is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
- ENST00000381317
- ENSP00000370718
- ENSG00000169093
- ENST00000381333
- ENSP00000370734
- ENST00000534940
- ENSP00000446410
- ASTML
- ASMTLX
- ASMTLY
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
protein domain | 0.85 | ||
tissue | 0.67 | ||
transcription factor | 0.61 | ||
cell type or tissue | 0.59 | ||
PubMedID | 0.58 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 7.96 (req: < 5)
Gene RIFs: 0 (req: <= 3)
Antibodies: 187 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 7.96 (req: >= 5)
Gene RIFs: 0 (req: > 3)
Antibodies: 187 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 2
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0