| Tbio | Apolipoprotein M |
Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid.
The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene. [provided by RefSeq, Jan 2012]
The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene. [provided by RefSeq, Jan 2012]
Comments
| Disease | Target Count | P-value |
|---|---|---|
| ependymoma | 4679 | 1.9e-14 |
| medulloblastoma | 720 | 2.7e-08 |
| osteosarcoma | 7950 | 4.9e-04 |
| nephrosclerosis | 333 | 1.8e-02 |
| pancreatic ductal adenocarcinoma liver metastasis | 1962 | 3.2e-02 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| chronic kidney disease | 90 | 4.318 | 2.2 |
| Atherosclerosis | 291 | 3.82 | 1.9 |
| Coronary artery disease | 268 | 3.331 | 1.7 |
| diabetes mellitus | 1728 | 3.235 | 1.6 |
| Disease | log2 FC | p |
|---|---|---|
| ependymoma | 1.300 | 1.9e-14 |
| medulloblastoma | 1.200 | 2.7e-08 |
| nephrosclerosis | -1.676 | 1.8e-02 |
| osteosarcoma | -1.260 | 4.9e-04 |
| pancreatic ductal adenocarcinoma liver m... | -1.652 | 3.2e-02 |
