Tbio ZFPL1 Zinc finger protein-like 1

Protein Summary

Description

Required for cis-Golgi integrity and efficient ER to Golgi transport. Involved in the maintenance of the integrity of the cis-Golgi, possibly via its interaction with GOLGA2/GM130.

Uniprot Accession IDs

• O95159
• A8K7E9
• O14616
• Q9UID0

Gene Name

• ZFPL1

Ensembl ID

• ENST00000294258
• ENSP00000294258
• ENSG00000162300

Symbol

• MCG4
• D11S750

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	0.97
histone modification site profile	0.89
interacting protein	0.85
co-expressed gene	0.65
transcription factor binding site profile	0.64

Protein Classes

PANTHER Classes

Protein / Transcription Factor / Zinc Finger Transcription Factor / Zinc Finger Protein-like 1

DTO Classes

Protein / Transcription Factor / Zinc Finger Transcription Factor / Zinc Finger Protein-like 1

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.18   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 106   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.18   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 106   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0