SLCO2B1
Solute carrier organic anion transporter family member 2B1
Protein Summary
Mediates the Na(+)-independent transport of organic anions such as taurocholate, the prostaglandins PGD2, PGE1, PGE2, leukotriene C4, thromboxane B2 and iloprost. This locus encodes a member of the organic anion-transporting polypeptide family of membrane proteins. The protein encoded by this locus may function in regulation of placental uptake of sulfated steroids. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2010]
- ENST00000428359
- ENSP00000388912
- ENSG00000137491
- ENST00000454962
- ENSP00000389653
- KIAA0880
- OATP2B1
- OATPB
- SLC21A9
- OATPB
- OATP-B
- OATP2B1
- SLC21A9
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
drug | 0.97 | ||
cell type or tissue | 0.68 | ||
transcription factor | 0.67 | ||
disease perturbation | 0.62 | ||
cell line | 0.61 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 224.33 (req: < 5)
Gene RIFs: 65 (req: <= 3)
Antibodies: 98 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 224.33 (req: >= 5)
Gene RIFs: 65 (req: > 3)
Antibodies: 98 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 5
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligands: 2
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 1