Tbio SCGN Secretagogin

Protein Summary

Description

The encoded protein is a secreted calcium-binding protein which is found in the cytoplasm. It is related to calbindin D-28K and calretinin. This protein is thought to be involved in KCL-stimulated calcium flux and cell proliferation. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• O76038
• A8K0B2
• Q5VV44
• Q96QV7
• Q9UJF6

Gene Name

• SCGN

Ensembl ID

• ENST00000377961
• ENSP00000367197
• ENSG00000079689

Symbol

• SECRET
• SEGN
• CALBL
• SECRET
• setagin
• DJ501N12.8

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.68
trait	0.61
PubMedID	0.59
gene perturbation	0.58
tissue	0.54

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 106.86   (req: < 5)

Gene RIFs: 19   (req: <= 3)

Antibodies: 306   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 106.86   (req: >= 5)

Gene RIFs: 19   (req: > 3)

Antibodies: 306   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0