| Tdark | Protein phosphatase 1 regulatory subunit 37 |
Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes.
Comments
| Disease | Target Count | P-value |
|---|---|---|
| atypical teratoid / rhabdoid tumor | 5112 | 8.6e-07 |
| medulloblastoma, large-cell | 6241 | 1.2e-06 |
| osteosarcoma | 7950 | 1.0e-04 |
| glioblastoma | 5792 | 4.1e-04 |
| adult high grade glioma | 3801 | 6.8e-04 |
| Disease | Target Count | Z-score | Confidence |
|---|---|---|---|
| Alzheimer's disease | 658 | 0.0 | 3.0 |
| Disease | log2 FC | p |
|---|---|---|
| adult high grade glioma | -1.500 | 6.8e-04 |
| atypical teratoid / rhabdoid tumor | -1.400 | 8.6e-07 |
| glioblastoma | -1.300 | 4.1e-04 |
| medulloblastoma, large-cell | -1.800 | 1.2e-06 |
| osteosarcoma | -1.071 | 1.0e-04 |
| Species | Source | Disease |
|---|---|---|
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| OMA EggNOG | ||
| Inparanoid OMA EggNOG | ||
| Inparanoid EggNOG | ||
| Inparanoid EggNOG | ||
| OMA EggNOG | ||
| OMA EggNOG |
MEIAPQEAPPVPGADGDIEEAPAEAGSPSPASPPADGRLKAAAKRVTFPSDEDIVSGAVEPKDPWRHAQN 1 - 70 VTVDEVIGAYKQACQKLNCRQIPKLLRQLQEFTDLGHRLDCLDLKGEKLDYKTCEALEEVFKRLQFKVVD 71 - 140 LEQTNLDEDGASALFDMIEYYESATHLNISFNKHIGTRGWQAAAHMMRKTSCLQYLDARNTPLLDHSAPF 141 - 210 VARALRIRSSLAVLHLENASLSGRPLMLLATALKMNMNLRELYLADNKLNGLQDSAQLGNLLKFNCSLQI 211 - 280 LDLRNNHVLDSGLAYICEGLKEQRKGLVTLVLWNNQLTHTGMAFLGMTLPHTQSLETLNLGHNPIGNEGV 281 - 350 RHLKNGLISNRSVLRLGLASTKLTCEGAVAVAEFIAESPRLLRLDLRENEIKTGGLMALSLALKVNHSLL 351 - 420 RLDLDREPKKEAVKSFIETQKALLAEIQNGCKRNLVLAREREEKEQPPQLSASMPETTATEPQPDDEPAA 421 - 490 GVQNGAPSPAPSPDSDSDSDSDGEEEEEEEGERDETPCPALVPPTDSLGPGDRSPPGSPSTPTEQRISVS 491 - 560 SPGRGHKVFVVTRVESPPERAEPPASPTPPSPPPPPSPPASPSLPPAGAIDTRDTGSSEPQPPPEPPRSG 561 - 630 PPLPNGLKPEFALALPPEPPPGPEVKGGSCGLEHELSCSKNEKELEELLLEASQESGQETL 631 - 691 //
