Tdark | Protein phosphatase 1 regulatory subunit 37 |
Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes.
Comments
Disease | Target Count | P-value |
---|---|---|
atypical teratoid / rhabdoid tumor | 4369 | 8.59208286094636E-7 |
medulloblastoma, large-cell | 6234 | 1.18624520569136E-6 |
osteosarcoma | 7933 | 1.00943142360477E-4 |
glioblastoma | 5572 | 4.07011189989632E-4 |
adult high grade glioma | 2148 | 6.79344943886092E-4 |
Disease | Target Count | Z-score | Confidence |
---|---|---|---|
Alzheimer's disease | 644 | 0.0 | 2.0 |
Disease | log2 FC | p |
---|---|---|
osteosarcoma | -1.071 | 0.000 |
atypical teratoid / rhabdoid tumor | -1.400 | 0.000 |
glioblastoma | -1.300 | 0.000 |
medulloblastoma, large-cell | -1.800 | 0.000 |
adult high grade glioma | -1.500 | 0.001 |
Species | Source |
---|---|
Chimp | OMA EggNOG |
Macaque | OMA EggNOG |
Mouse | OMA EggNOG Inparanoid |
Rat | OMA EggNOG Inparanoid |
Dog | OMA EggNOG Inparanoid |
Horse | OMA EggNOG |
Cow | OMA EggNOG Inparanoid |
Opossum | OMA EggNOG Inparanoid |
Anole lizard | OMA EggNOG Inparanoid |
Xenopus | OMA EggNOG |
C. elegans | EggNOG Inparanoid |
Fruitfly | EggNOG Inparanoid |
MEIAPQEAPPVPGADGDIEEAPAEAGSPSPASPPADGRLKAAAKRVTFPSDEDIVSGAVEPKDPWRHAQN 1 - 70 VTVDEVIGAYKQACQKLNCRQIPKLLRQLQEFTDLGHRLDCLDLKGEKLDYKTCEALEEVFKRLQFKVVD 71 - 140 LEQTNLDEDGASALFDMIEYYESATHLNISFNKHIGTRGWQAAAHMMRKTSCLQYLDARNTPLLDHSAPF 141 - 210 VARALRIRSSLAVLHLENASLSGRPLMLLATALKMNMNLRELYLADNKLNGLQDSAQLGNLLKFNCSLQI 211 - 280 LDLRNNHVLDSGLAYICEGLKEQRKGLVTLVLWNNQLTHTGMAFLGMTLPHTQSLETLNLGHNPIGNEGV 281 - 350 RHLKNGLISNRSVLRLGLASTKLTCEGAVAVAEFIAESPRLLRLDLRENEIKTGGLMALSLALKVNHSLL 351 - 420 RLDLDREPKKEAVKSFIETQKALLAEIQNGCKRNLVLAREREEKEQPPQLSASMPETTATEPQPDDEPAA 421 - 490 GVQNGAPSPAPSPDSDSDSDSDGEEEEEEEGERDETPCPALVPPTDSLGPGDRSPPGSPSTPTEQRISVS 491 - 560 SPGRGHKVFVVTRVESPPERAEPPASPTPPSPPPPPSPPASPSLPPAGAIDTRDTGSSEPQPPPEPPRSG 561 - 630 PPLPNGLKPEFALALPPEPPPGPEVKGGSCGLEHELSCSKNEKELEELLLEASQESGQETL 631 - 691 //
PMID | Year | Title |
---|---|---|
23565137 | 2013 | SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians. |
23186163 | 2013 | Toward a comprehensive characterization of a human cancer cell phosphoproteome. |
19389623 | 2009 | Docking motif-guided mapping of the interactome of protein phosphatase-1. |
18669648 | 2008 | A quantitative atlas of mitotic phosphorylation. |
15489334 | 2004 | The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
15231748 | 2004 | Functional proteomics mapping of a human signaling pathway. |
15057824 | 2004 | The DNA sequence and biology of human chromosome 19. |
12477932 | 2002 | Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |
12107411 | 2002 | Expressed sequence tag analysis of human retina for the NEIBank Project: retbindin, an abundant, novel retinal cDNA and alternative splicing of other retina-preferred gene transcripts. |
11853319 | 2001 | Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. |