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Tdark Protein phosphatase 1 regulatory subunit 37

Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes.

 Comments

Property Summary

NCBI Gene PubMed Count 6
PubMed Score 0.00

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (2)

Disease Target Count Z-score Confidence
Alzheimer's disease 658 0.0 3.0

Expression

  Differential Expression (5)

Disease log2 FC p
adult high grade glioma -1.500 6.8e-04
atypical teratoid / rhabdoid tumor -1.400 8.6e-07
glioblastoma -1.300 4.1e-04
medulloblastoma, large-cell -1.800 1.2e-06
osteosarcoma -1.071 1.0e-04

Synonym

Accession O75864 B5MDA4 Q8IWK3 Q8TF16
Symbols LRRC68

Gene

PPP1R37

PANTHER Protein Class (2)

  Ortholog (1)

Species Source Disease
Chimp OMA EggNOG

 UniProt Keyword (7)

 GO Function (2)

 GO Process (1)

 Compartment GO Term (1)

 GWAS Trait (1)

 HCA RNA Cell Line (56)

See all...

AA Sequence 

MEIAPQEAPPVPGADGDIEEAPAEAGSPSPASPPADGRLKAAAKRVTFPSDEDIVSGAVEPKDPWRHAQN      1 - 70
VTVDEVIGAYKQACQKLNCRQIPKLLRQLQEFTDLGHRLDCLDLKGEKLDYKTCEALEEVFKRLQFKVVD     71 - 140
LEQTNLDEDGASALFDMIEYYESATHLNISFNKHIGTRGWQAAAHMMRKTSCLQYLDARNTPLLDHSAPF    141 - 210
VARALRIRSSLAVLHLENASLSGRPLMLLATALKMNMNLRELYLADNKLNGLQDSAQLGNLLKFNCSLQI    211 - 280
LDLRNNHVLDSGLAYICEGLKEQRKGLVTLVLWNNQLTHTGMAFLGMTLPHTQSLETLNLGHNPIGNEGV    281 - 350
RHLKNGLISNRSVLRLGLASTKLTCEGAVAVAEFIAESPRLLRLDLRENEIKTGGLMALSLALKVNHSLL    351 - 420
RLDLDREPKKEAVKSFIETQKALLAEIQNGCKRNLVLAREREEKEQPPQLSASMPETTATEPQPDDEPAA    421 - 490
GVQNGAPSPAPSPDSDSDSDSDGEEEEEEEGERDETPCPALVPPTDSLGPGDRSPPGSPSTPTEQRISVS    491 - 560
SPGRGHKVFVVTRVESPPERAEPPASPTPPSPPPPPSPPASPSLPPAGAIDTRDTGSSEPQPPPEPPRSG    561 - 630
PPLPNGLKPEFALALPPEPPPGPEVKGGSCGLEHELSCSKNEKELEELLLEASQESGQETL             631 - 691
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Text Mined References (11)

PMID Year Title