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Tbio Mammaglobin-B

May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones.

 Comments

Property Summary

NCBI Gene PubMed Count 30
PubMed Score 210.56
PubTator Score 205.43

Knowledge Summary

Patent

No data available

TINX Plot

  Disease (1)

Expression

  Differential Expression (16)

Disease log2 FC p
active Crohn's disease 1.593 2.3e-02
Atopic dermatitis -1.700 1.1e-02
Breast cancer -2.700 2.7e-04
colon cancer -2.000 1.2e-02
cutaneous lupus erythematosus -3.800 1.7e-04
Endometriosis -1.220 3.3e-02
ependymoma 1.500 1.6e-02
head and neck cancer and chronic obstruc... -1.200 2.9e-02
intraductal papillary-mucinous adenoma (... 3.600 7.2e-04
intraductal papillary-mucinous neoplasm ... 2.800 2.0e-02
lung carcinoma 1.200 4.4e-05
nasopharyngeal carcinoma -2.300 3.8e-04
ovarian cancer 4.400 2.1e-06
pituitary cancer -2.600 2.5e-04
psoriasis -1.700 6.8e-06
pterygium -1.500 4.2e-03

Synonym

Accession O75556
Symbols LPHC
LPNC
MGB2
UGB3

Gene

SCGB2A1

  Ortholog (7)

Species Source Disease
Inparanoid OMA EggNOG
OMA EggNOG
OMA EggNOG
Inparanoid OMA EggNOG
Inparanoid EggNOG
OMA EggNOG
Inparanoid OMA EggNOG

 UniProt Keyword (5)

 GO Function (1)

 GO Component (1)

 GO Process (1)

 Compartment GO Term (4)

 GWAS Trait (2)

 HCA RNA Cell Line (14)

See all...

Protein-protein Interaction (57)

CANX   LARGE2   LARGE1   PLXNA3   INSR   HLA-A   GLB1L   TENM3   TOR3A   TPST2   PLXNB2   POGLUT1   PCYOX1L   ARSK   EXT1   CNTNAP3   MOGS   SLC27A2   BCHE   COL14A1   MAN2A1   GPC4   NRAS   LMF2   EOGT   B4GALT6   EXTL3   CHST10   COL6A1   NDST2   NDST1   PCYOX1   GCNT1   FSTL1   NXPE3   SCCPDH   IL17RA   MGAT5   NDC1   RDH13   CERCAM   WDR54   EMC3   HPSE   GALNT6   NAGLU   BACE1   PLA2G15   PLTP   SELENON   EPHB4   TMEM62   PDGFC   PRAF2   LAMA3   MINPP1   ECEL1  

Gene RIF (16)

AA Sequence 

MKLLMVLMLAALLLHCYADSGCKLLEDMVEKTINSDISIPEYKELLQEFIDSDAAAEAMGKFKQCFLNQS      1 - 70
HRTLKNFGLMMHTVYDSIWCNMKSN                                                  71 - 95
//

Text Mined References (32)

PMID Year Title