Tbio | Mammaglobin-B |
May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones.
Comments
Disease | Target Count | P-value |
---|---|---|
ovarian cancer | 8492 | 2.1334909652339E-6 |
posterior fossa group B ependymoma | 1530 | 4.7333419817555E-6 |
psoriasis | 6685 | 3.47536334081698E-5 |
lung carcinoma | 2844 | 4.36831662136988E-5 |
cutaneous lupus erythematosus | 1056 | 1.7038446068062E-4 |
pituitary cancer | 1972 | 2.52614710466572E-4 |
Breast cancer | 3099 | 2.66096751338273E-4 |
nasopharyngeal carcinoma | 1056 | 3.83921950712978E-4 |
intraductal papillary-mucinous adenoma (IPMA) | 2956 | 7.15871096015546E-4 |
colon cancer | 1475 | 0.00169296781235065 |
pterygium | 74 | 0.00420548167160317 |
Atopic dermatitis | 944 | 0.0108184887799087 |
intraductal papillary-mucinous neoplasm (IPMN) | 3289 | 0.0200725204126913 |
active Crohn's disease | 918 | 0.0231406422469599 |
head and neck cancer and chronic obstructive pulmonary disease | 237 | 0.0288214038219401 |
Endometriosis | 535 | 0.0326214271916233 |
Disease | log2 FC | p |
---|---|---|
psoriasis | -4.300 | 0.000 |
cutaneous lupus erythematosus | -3.800 | 0.000 |
posterior fossa group B ependymoma | 3.600 | 0.000 |
Atopic dermatitis | -1.700 | 0.011 |
intraductal papillary-mucinous adenoma (... | 3.600 | 0.001 |
intraductal papillary-mucinous neoplasm ... | 2.800 | 0.020 |
colon cancer | -2.100 | 0.002 |
active Crohn's disease | 1.593 | 0.023 |
nasopharyngeal carcinoma | -2.300 | 0.000 |
Endometriosis | -1.220 | 0.033 |
lung carcinoma | 1.200 | 0.000 |
Breast cancer | -2.700 | 0.000 |
pterygium | -1.500 | 0.004 |
ovarian cancer | 4.400 | 0.000 |
pituitary cancer | -2.600 | 0.000 |
head and neck cancer and chronic obstruc... | -1.200 | 0.029 |
Accession | O75556 |
Symbols |
LPHC LPNC MGB2 UGB3 |
Species | Source |
---|---|
Chimp | OMA EggNOG |
Mouse | OMA EggNOG Inparanoid |
Rat | OMA EggNOG Inparanoid |
Horse | OMA EggNOG |
Cow | OMA EggNOG Inparanoid |
Pig | EggNOG Inparanoid |
PMID | Text |
---|---|
25425335 | The commonly used breast carcinoma biomarkers vary in their prognostic implications. GCDFP-15 independently indicated a favourable prognosis. GATA-3 and MGB were not associated with outcome. |
24706379 | Results indicate that the quantitative analysis of h-MAM mRNA is a useful tool for detecting CTCs in breast cancer patients. |
24603286 | The data indicate that MGB1, MGB2 and LIPB mRNAs are expressed at low levels in human tissues but basal expression is upregulated in ovarian cancer. |
24585249 | Results indicated that SCGB2A1 represented a novel, prognostic factor for colorectal cancer, and its expression correlated with chemoresistance, radioresistance and cancer cell stemness. |
23807163 | SCGB2A1 is a top differentially expressed gene in all major histological types of ovarian cancers. |
23332923 | MGB has the highest expression in HER2-overexpressing breast cancers and may be a potentially useful marker for this subtype. |
20306663 | Data show that plasma mammaglobin mRNA alone or in combination with CA15.3 (CD227) may be used as a valuable noninvasive approach for the diagnosis and the detection of metastasis in breast cancer at the time of diagnosis. |
19635143 | MGB-2 expression characterizes less aggressive forms of EOC and is correlated with a favorable outcome |
18416968 | Expression levels of mammaglobins A and B in nasal polyps are not different between patients with and without AR |
18021217 | MGB-2 is highly expressed in endometrioid endometrial cancer [EEC], particularly in well- and moderately differentiated tumors, and may represent a novel molecular marker for EEC |
More... |
PMID | Year | Title |
---|---|---|
25946035 | 2015 | Human Basal Tear Peptidome Characterization by CID, HCD, and ETD Followed by in Silico and in Vitro Analyses for Antimicrobial Peptide Identification. |
25425335 | 2015 | GATA-binding protein 3, gross cystic disease fluid protein-15 and mammaglobin have distinct prognostic implications in different invasive breast carcinoma subgroups. |
24823311 | 2014 | Genome-wide association study of plasma N6 polyunsaturated fatty acids within the cohorts for heart and aging research in genomic epidemiology consortium. |
24706379 | 2014 | The clinical utility of circulating tumor cells in breast cancer patients: detection by a quantitative assay of h-MAM gene expression. |
24603286 | 2014 | Differential expression of secretoglobins in normal ovary and in ovarian carcinoma--overexpression of mammaglobin-1 is linked to tumor progression. |
24585249 | 2014 | SCGB2A1 is a novel prognostic marker for colorectal cancer associated with chemoresistance and radioresistance. |
23807163 | 2013 | Mammaglobin B (SCGB2A1) is a novel tumour antigen highly differentially expressed in all major histological types of ovarian cancer: implications for ovarian cancer immunotherapy. |
23580065 | 2013 | Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy. |
23332923 | 2013 | Expression of mammaglobin and gross cystic disease fluid protein-15 in breast carcinomas. |
22664934 | 2012 | Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach. |
More... |