Protein Summary
May be involved in transcriptional regulation. This gene encodes a protein with two C2H2 zinc finger motifs and a score-and-three (23)-amino acid peptide repeat (STPR) domain. The STPR domain of the encoded protein binds to double stranded DNA and may also contain a nuclear localization signal, suggesting that this protein interacts with chromosomal DNA. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
- ENST00000425432
- ENSP00000398089
- ENSG00000102984
- ENST00000565601
- ENSP00000455648
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
transcription factor | 0.62 | ||
disease perturbation | 0.56 | ||
histone modification site profile | 0.56 | ||
gene perturbation | 0.55 | ||
transcription factor binding site profile | 0.55 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 2.07 (req: < 5)
Gene RIFs: 1 (req: <= 3)
Antibodies: 86 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 2.07 (req: >= 5)
Gene RIFs: 1 (req: > 3)
Antibodies: 86 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 4
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0